Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 37 for “"cerebral arteries"”.
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Signal Transduction and Gene Regulation in Cerebral Arteries Following Ischemia
… the molecular events that take place in the cerebral arteries following a stroke. The degree and temporal course of reperfusion following a stroke is pivotal for the survival of the neuronal tissue in the penumbra. Previous investigations have revealed upregulation of contractile receptors, a …
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Interaction between Adrenergic and Nitric Oxide-releasing Nerves in Cerebral Arteries
… of ischemia so much that interruption of cerebral blood flow by 5 sec can cause syncope, with irreversible tissue damage if the ischemia last a few minutes. In this respect, the body has an imperative duty of ensuring constant and adequate blood supply to the brain. It does so through a …
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Endothelin-1 and Hypoxic Vascular Remodeling in Ovine Fetal Cerebral Arteries
… in an ETAdependent manner in Middle Cerebral Arteries (MCAs). ET-1 also exerts trophic effects on ovine fetal cerebrovasculature in organ culture in a PKC-dependent manner by inducing hypertrophy and increasing medial thicknesses, more in normoxic than hypoxic MCAs. ET-1-induced …
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Patient-Specific Computer Modeling of Blood Flow in Cerebral Arteries With Aneurysm and Stent
… computer modeling of blood flow in cerebral arteries with aneurysm and stent. These techniques are used in conjunction with the core computational technique, which is the space–time version of the variational multiscale (VMS) method and is called “DST/SST-VMST.” The special …
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Role of Protein Kinase G in Regulating Vascular Tone in Hypoxic Ovine Cerebral Arteries
… in these conditions, we used carotid and middle cerebral arteries from normoxic and chronically hypoxic fetal and adult sheep. These arteries were denuded of endothelium and used in concentration-response relations using 5-HT as a contractant and measured contractile force. To measure the …
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The Role of VEGF and Smooth Muscle Phenotype in Hypoxic Remodeling of Ovine Carotid and Cerebral Arteries
<p>Arteries are a dynamic tissue with multiple cell types that incorporate systemic and local factors to maintain homeostasis. Hypoxia stimulates capillary angiogenesis to effectively match metabolic demand with perfusion. With chronic hypoxia, vascular remodeling of even large vessels can occur. …
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Étude des liens entre les mesures quantitatives de la vascularisation cérébrale, les fonctions cognitives et la neuropathologie dans la maladie d’Alzheimer
… between 1) the diameters of the posterior cerebral arteries, 2nd segment (ACP2) and of the anterior choroidal arteries (AchA) and the Clinical Dementia Rating Scale – Sum of Boxes (CDR-SB) and 2) the diameters and the volumes of cerebral arteries and i) cognition; ii) AD neuropathology, …
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Vascular receptor changes in ischemic stroke
… vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. In addition, rat cerebral arteries and arterial smooth muscle cells were cultured for further analysis of cerebrovascular receptor …
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Postnatal Maturation Modulates Cerebrovascular Myogenic Tone
… maintain pressure-evoked myogenic tone in rat cerebral blood vessels. To test this hypothesis, pressure-induced myogenic tone and changes in artery wall ([Ca2+]i) were measured simultaneously in isolated endothelium denuded, fura-2 loaded middle cerebral arteries (MCA) from pup (PI4) and adult …
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Cerebral Microcirculatory Effects of Maturation
… (4B) branches of newborn and adult sheep middle cerebral arteries, 5-HT2 serotonergic receptors mediate contractile responses to serotonin and that alpha-1 adrenergic receptors mediate contractile responses to norepinephrine. In addition, tissue sensitivity to 5-HT and NE decreases significantly …
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Do dreams protect sleep? Testing the Freudian hypothesis of the function of dreams
… thrombotic stroke in the region of the posterior cerebral arteries was compared with that of patients with the same pathology who had not experienced dream loss. Using medical records, structural neuro-imaging, clinical interviews, neuropsychological testing, analysis of subjective sleep quality, …
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Comprehensive geometric modeling of human cerebral vasculature for quantitative vascular analysis
… and structured geometric model of human cerebral vasculature for quantitative anatomical analysis. We first proposed a general and structured geometric representation of the interconnected vascular network as a framework. We then described an image processing pipeline for the segmentation …
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Protein Trafficking of BK Channel β1 Subunits in Cerebral Artery Myocytes
… and mental dysfunction. During hypertension, cerebral arteries have high myogenic tone and are less responsive to vasodilators, including nitric oxide (NO). The regulation of arterial contractility by BK channels is altered during hypertension, although mechanisms involved are also unclear. …
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Funktionelle Untersuchungen mit der transkraniellen Dopplersonographie bei Gesunden und Aphasikern
… sonography blood flow changes of both middle cerebral arteries were measured simultaneously during cognitive stimulation with special consideration of the interhemispherical distribution, in order to evaluate functional recompensation mechanisms after cerebral damage. Test paradigms, which …
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CT angiographic detection of cerebral aneurysms in patients with subarachnoid haemorrhage in a South African institution
… location, morphology and size characteristics of cerebral aneurysms in patients presenting to Groote Schuur hospital with either subarachnoid haemorrhage or 3 rd nerve palsy have not been established by a formal audit. Objectives To determine the patient demographics, frequency of CT angiographic …
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T-type Calcium Channels in Arterial Smooth Muscle: Activity, Regulation and Function
… subtypes (i.e. CaV3.1 and CaV3.2). In rat cerebral arteries, T-type channel activity was shown to be a regulatory target of vasodilatory kinases. In particular, β-adrenergic receptors and downstream activation of protein kinase A selectively inhibited CaV3.2 currents. Nitric oxide …
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Computational model of thrombosis in cerebral aneurysms for predicting clotting outcomes in flow diverter treated patient-derived geometries validated with novel PIV-based ln vitro clotting flow experiment
… number of computational models of thrombosis in cerebral aneurysms designed with consideration towards clinical use and research. Many thrombosis models include complicated clotting mechanisms, which can be computationally expensive, and present a challenge to comprehensively validate in vitro …
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Semi-autonomous Magnetic Manipulation for Endovascular Navigation
… geometrical complexity, navigation inside the cerebral arteries becomes challenging as the destination moves further toward the distal region of the brain. Magnetic manipulation is one solution that can resolve this difficulty. By utilizing magnetic force and torque, magnetic manipulation …
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Intima-Media-Thickness (IMT) bei Patienten mit vertebrobasilären und karotidalen Stenosen/Verschlüssen
… artery) and the localisation in the carortid arteries of the IMT are already illuminated. It is not known actually, if different types of atherosclerosis are accompanied by a different IMT. The purpose of the study was to invesigate the IMT in patients with stenoses or occlusions in the …
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