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Showing 1 to 3 of 3 for “"ceramide transfer protein"”.
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Structural Basis for the Regulation of the Ceramide Transfer Protein
Ceramide, a central intermediate in sphingolipid metabolism, is synthesized at the endoplasmic reticulum (ER) and transferred to the Golgi by the ceramide transfer (CERT) protein for conversion to sphingomyelin (SM). CERT is a multi-domain protein that contains an amino terminal pleckstrin homology …
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The Middle Region is Required for Phosphorylation Regulation of Ceramide Transfer Protein
The trafficking of ceramide from endoplasmic reticulum (ER), where it is synthesized, to the Golgi for sphingomyelin synthesis is mediated by the ceramide transfer protein (CERT) in a nonvesicular fashion. CERT is a cytosolic protein containing multiple domains and motifs. The START (steroidogenic …
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Structural and functional characterisation of pUL21, an α-herpesvirus phosphatase adaptor protein
… Virus infection is a complex process where viral proteins cooperate to exploit host cell metabolism while evading immune responses. Herpes simplex virus 1 (HSV-1) is a very prevalent human herpesvirus that causes life-long infection and is known to dramatically remodel the cellular environment …