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Showing 1 to 7 of 7 for “"cellulose ethers"”.
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Drug release from pellets and matrices based on cellulose ethers.
… t~~sis examines the use of hydro~yprol?ylmethylcellulose (HPM~) of di.tJer~nt VIScosities and ethylcellulose aqueous dispersion (Surelease), alone or m combination with each other, to control the release of metoclopramide hydrochloride or diclofenac sodium from coated pellets or matrices. The …
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Characterizing Interfacial and Bulk Interactions Between Cellulose Ethers and Bile Salts: Impact on In Vitro Lipid Digestion
… limiting the access of BS to the lipid surface. Cellulose ethers (CEs), surface-active dietary fibers and common food additives, might be promising ingredients to control lipid digestion either by creating surface layers around lipid droplets that hinder adsorption of BS, or by sequestering BS in …
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Regioselective Synthesis of Cellulose Derivatives
Cellulose is the most abundant polysaccharide on earth and it is relatively a simple homopolymer with three hydroxyl groups, differing only subtly in reactivity. The position of substitution has a powerful influence on physical properties of cellulose derivatives. To better understand the structure …
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Design and Synthesis of Complex and Fluorescent Labeled Cellulose-Based Derivatives for Orally Administered Drug Delivery Systems
Cellulose ethers are valuable matrices for drug-delivery systems (DDS), namely amorphous solid dispersions (ASD). ASD are efficient vehicles that can solubilize and stabilize poorly soluble drugs by increasing the time that it takes for drugs to crystallize, thereby allowing higher drug …
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Synthesis and characterization of fluorinated cellulose derivatives
The synthesis of fluorinated cellulose derivatives was pursued for the purpose of investigating the effects of fluorine on the interfacial properties of cellulose derivatives, in multiphase materials. Synthetic approaches included: 1) the replacement of hydroxyl groups on cellulose with fluorine …
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Design and development of drug delivery systems for immediate and sustained release utilizing hot melt extrusion
… by the FDA. Various polymers for example cellulose ethers (HEC, HPC and HPMC), hypermellose ester derivatives (HPMCAS and HPMCP) and acrylic polymer (Eudragit® EPO) with pH dependant solubility were examined for suitability as solubility enhancers for EFZ and processability in melt …
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Design and Synthesis of Cellulose Ether Derivatives for Oral Drug Delivery
Chemical modification of naturally occurring cellulose into ester and ether derivatives has been of growing interest due to inexhaustible cellulose resources, and to excellent properties and extremely broad applications of these derivatives. However, traditional esterification and etherification …