Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 125 for “"cell transplantation"”.
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Functionalised self-assembled peptide hydrogel for cell transplantation
Cell transplantation has provided a novel approach for the treatment of brain disorders due to its inherent ability to introduce replacement cells for tissue regeneration. The direct injection of the grafted cells via syringe administration represents the current administration strategy for …
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Functionalised self-assembled peptide hydrogel for cell transplantation
Cell transplantation has provided a novel approach for the treatment of brain disorders due to its inherent ability to introduce replacement cells for tissue regeneration. The direct injection of the grafted cells via syringe administration represents the current administration strategy for …
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Olfactory progenitor cell transplantation into the mammalian inner ear
A practical consideration in the development of cellular therapy technology for the inner ear is the development of an in vitro model for assessing the optimal conditions for successful application of cells. The first part of this thesis describes the adaptation of the cochleovestibular structure …
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Saliva and oral mucositis after hematopoietic stem cell transplantation
Contains fulltext : 225513.pdf (Publisher’s version ) (Open Access)
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Mucosal Barrier Injury, Innate Immunity, and Stem Cell Transplantation
Contains fulltext : 87189.pdf (Publisher’s version ) (Open Access)
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Donor lymphocyte infusion after allogeneic stem cell transplantation in children
… syndrome following allogeneic hematopoietic stem cell transplantation (allo HSCT). However, DLI is limited by the development of graft-versus-host disease (GVHD)and marrow aplasia, and the efficacy of DLIis not defined in children. So we evaluate DLI for last decade, and …
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Patients' experience before, during and after stem cell transplantation-phenomenological study
… life threatening treatment such as stem cell transplantation (SCT). The purpose of this study was to develop our understanding of the meaning SCT has for African-American, Latino, and Caucasian patients before, during, and after stem cell treatment. An extensive review of the literature …
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The Impacts of Sex and Myogenic Cell Transplantation on Collateral Capillary Arteriogenesis
… could be due to impaired collateralization. Cell transplantation is a potential treatment option to promote collateral arteriogenesis. Bone marrow derived stem cells are the main cell type that has been investigated, but they have had limited clinical success. Delivering a stem cell type …
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Improving Leukocyte Recovery Through Physiologically Relevant Oxygen Expansion after Hematopoietic Stem Cell Transplantation
… recovery of lymphocytes post hematopoietic stem cell transplantation (HCT) is correlated with positive patient outcome in treatments of hematologic disease. Few effective clinical therapies exist to enhance lymphocyte recovery, indicating a clear unmet need. Ex vivo expansion of umbilical cord …
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Cellular and Circuit Level Responses to Neural Stem Cell Transplantation in the Rodent Cortex
Neural stem cell (NSC) transplantation is a promising strategy for the treatment of neurological disease and injury. NSC transplants have been documented to exert both neurotrophic and immunomodulatory effects in pathological contexts, but grafted cells frequently remain undifferentiated. The …
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Analysis of Therapeutic Effect after Human Mesenchymal Stem Cell Transplantation in Ischemic Stroke Rat
Background and PURPOSE: Mesenchymal stem cells (MSCs) have recently been investigated as an attractive therapeutic tool for ischemic stroke because of their plasticity and availability. For the understanding of therapeutic effect of MSCs after transplantation in ischemic rats, changes in free fatty …
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Biohybrid Peripheral Neural Interfaces: Combining Cell Transplantation and Flexible Electronics for Functional Neurological Restoration
… for these conditions. Neuroprosthetics and cell transplantation are promising approaches to restore lost neurological function: the former aims to bypass the site of injury, connecting directly one part of the nervous system to another (or a prosthetic limb); while the latter aims to repair …
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Immunotolerance regeneration by T regulatory cells in autologous haematopoietic stem cell transplantation for multiple sclerosis
… system (CNS). Autologous haematopoietic stem cell transplantation (AHSCT) has received increasing attention in recent years as a therapeutic option for treatment refractory MS. AHSCT has been proposed to induce long-term remission by initiating an immune system “reboot” via the …
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Tumor immune escape in allogeneic stem cell transplantation: Releasing the brake on graft-versus-tumor immunity
Contains fulltext : 101020.pdf (Publisher’s version ) (Open Access)
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Lung Progenitor Cell Transplantation for Pulmonary Fibrosis and Ex Vivo Expansion of Patch-Forming EpCAM⁺CD31⁺ Cells
… interventions can slow disease progression, lung transplantation remains the only curative option—yet its use is limited by donor scarcity and poor post-transplant survival related to the procedure. Previous studies in our group demonstrated the lung regenerative potential of simple lung cell …
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Exploring Prevalence and Management of Anxiety in Children and Adolescents with Cancer or Undergoing Hematopoietic Stem Cell Transplantation
… with cancer or undergoing hematopoietic stem cell transplantation (HSCT), to estimate the burden of anxiety and to describe guideline recommendations for assessing and managing anxiety in this population. The three papers comprising this dissertation established several key findings, …
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Hematopoietic Stem Cell Threshold Sensing Controls Regulatory Pathways Facilitating Clinically Relevant Ex Vivo Expansion for Stem Cell Transplantation
<p>The ex vivo expansion of hematopoietic stem cells (HSCs) for transplantation has threefold importance: 1.) First, because of the rarity of stem cells there often isn’t a sufficient supply obtainable from common sources for larger children and adults. 2.) Secondly, patient morbidity and time to …
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Role of the Tcell genotype in the development of allogeneic responses after stem cell transplantation and cellular immunotherapy.
Contains fulltext : 19390.pdf (Publisher’s version ) (Open Access)
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Investigating three-dimensional (3D) gelatin methacryloyl (GelMA) hydrogel as a potential scaffold for cell transplantation in Huntington's disease
… CAG repeats that form mutant huntingtin protein. Cell replacement therapy (CRT) offers a potential pathway to treat HD by replacing the striatal neurons lost during the disease progression with healthy ones. The emergence of cell reprogramming technology offers a powerful tool to generate an …
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