Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"cell surface proteomics"”.
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Investigating the function of the hereditary spastic paraplegia protein spastin in the endomembrane system
… well as to analyse the resulting effects on the cell surface proteome. Through this work, I have shown that spastin functions to mediate the fission of endosomal recycling tubule and have confirmed spastin’s localisation to ER exit sites, but show using synchronised secretion assays that spastin …
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RNA Therapeutics for Fibrolamellar Hepatocellular Carcinoma
<p>Fibrolamellar hepatocellular carcinoma (FLC) is a rare liver cancer characterized by a recurrent fusion of the heat shock protein DNAJB1 and the catalytic subunit of protein kinase A (PRKACA). Due to limited efficacy of conventional treatments such as chemotherapy and radiation my work explored …