Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"cell regulator"”.
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Trim24 In Normal & Malignant Hematopoiesis
… options include chemotherapy and allogeneic stem cell transplants, which also involves high-dose chemotherapy or radiation treatment. These options have little success in the long-run, as only an estimated 26% of patients survive five years post-diagnosis. In efforts to address this low survival …
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Targeting Cox-2 and Rank In Aggressive Breast Cancers: Inflammatory Breast Cancer and Triple-Negative Breast Cancer
… elevated COX-2 levels in EGFR-positive IBC cells and a significant correlation between COX-2 and EGFR gene expression in IBC tumors. How COX-2 linked to CSCs and regulates IBC progression is not well understood. We hypothesize COX-2 to be critical for IBC progression through regulation of …
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Targeting Cox-2 and Rank In Aggressive Breast Cancers: Inflammatory Breast Cancer and Triple-Negative Breast Cancer
… elevated COX-2 levels in EGFR-positive IBC cells and a significant correlation between COX-2 and EGFR gene expression in IBC tumors. How COX-2 linked to CSCs and regulates IBC progression is not well understood. We hypothesize COX-2 to be critical for IBC progression through regulation of …
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Interleukin-10 Suppresses Mast Cell IgE Receptor Expression And Signaling In Vitro And In Vivo
Background: Mast cells are known for their role in allergy, asthma, and systemic anaphylaxis, and have been shown to play a role in inflammatory disease. Interleukin-10 can regulate inflammatory responses both in vitro and in vivo, and may be a natural regulator of mast cell activation.Objective: …
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MYC transcriptional functions controlling epidermal stem cell self-renewal and differentiation
… has long been recognized as an important stem cell regulator, yet its direct biological contributions have been difficult to determine. MYC activation can induce pleiotropic phenotypes and mediates cellular functions as opposing as cell growth and proliferation, metabolism, differentiation and …
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Positive and negative immunoregulation of normal and tumor-bearing mouse T cell blastogenesis
… lymphocyte reaction (MLR) as a correlate of cell-mediated immunity, an examination was made of positive and negative blastogenic immunoregulation by syngeneic peritoneal macrophages (M<sub>Φ</sub>) and splenic T cells from tumor-bearing mice (TBM). As analysis of T cell proliferative response …