Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"cell fate acquisition"”.
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Interaction between form and fate during human neural development
Genetics instructs on cell differentiation. Controlled cell differentiation over time and space determines the formation of complex tissue structures. Tissue architecture is permissive to tissue function. Little is known about whether tissue architecture influences cell fate acquisition. We sought …
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SMAD2/3 - FOXH1 regulation during cell cycle progression upon differentiation
… and to later produce the correct amounts of each cell type. While the characteristics of cell cycle regulation in pluripotent and differentiated cells have been well described, the way they coordinate cell fate acquisition is only beginning to be elucidated. Indeed, the activity of TGFβ signalling …
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Mechanisms of bullseye boundary formation in Hibiscus trionum petal patterning
… striking patterns combining pigmentation, cell shape and cuticular ornamentation. These patterns contribute to plant-pollinator interactions but how spatial control of cell fate specification is achieved across the petal epidermis remains obscure. Hibiscus trionum is an emerging model …
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Molecular and Functional Characterization of TrkC Alternative Splicing Regulation and its Impact on the Fate Acquisition of Cortical Projection Neurons
The astonishing cellular diversity and finely tuned neuroanatomy of the cerebral cortex motivates sustained research efforts on the mechanisms that give rise to this intricate tissue. To enable the higher cognitive functions of mammals, various subtypes of cortical projection neurons, distributed …
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A Developmental Pathway for Epithelial-to-Motoneuron Transformation in C. Elegans
… animal development, neurons and neuron-like cells are generated from progenitor cells that often line tubes. For example, in the developing spinal cord, basal processes of radial glial stem cells line the fluid-filled spinal canal. Notch/Delta signaling is implicated in the differentiation of …