Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"cell envelope stress"”.
-
Intramembrane signal transduction and cell envelope stress response in <i>Bacillus subtilis</i>
… für ein Bakterium lebenswichtig. Die Zellhüllstress-Antwort in Bacillus subtilis wird durch sieben signaltransduzierende Systeme vermittelt, zu denen drei ECF-sigma-Faktoren und vier Zweikomponentensysteme gehören. Eines dieser Zweikomponentensysteme ist das LiaRS-System, welches auf …
-
A role for a predicted E. coli inner membrane lipoprotein in cell envelope integrity
… is the possession of a double-membraned cell envelope. The outer membrane provides an additional layer of protection against hydrophobic molecules including antibiotics, contributing to the multidrug resistance crisis. The Gram-negative membrane is composed of phospholipids, glycolipids, …
-
Understanding the Genome-Wide Response of Streptomyces coelicolor to the Glycopeptide Antibiotic Teicoplanin
… the terminal residues, D-Alanyl-D-Alanine on the cell wall peptidoglycan intermediate lipid II, interfering with peptidoglycan biosynthesis and weakening the cell wall. A general resistance mechanism to these antibiotics requires a core set of genes, vanRSHAX, that detect a glycopeptide (VanS) and …
-
Investigation of Bacillus subtilis Sigma Factor Dynamics Using Improved Single Cell Tools
… It has been shown previously that single cell approaches can reveal hidden dynamics in sigma factor activation. Here, we investigate the single cell response dynamics of the \textit{B. subtilis} extracytoplasmic function sigma factors, which are an important part of the cell envelope …
-
Structure and function analysis of the natural product plantazolicin, a bacillus anthracis-specific antibiotic
… significant upregulation of genes within the cell envelope stress response. Using fluorescence microscopy, PZN localizes to distinct ~200 nm wide foci within the envelope; furthermore, like other cell envelope-acting compounds, PZN depolarizes the B. anthracis membrane. Upon selection and …
-
A Systematic Method for Enhanced Expression of Alcohol Dehydrogenases in Escherichia coli
… design was further developed to improve the cellular density of the high pH system through fitness modifications to the E. coli strains of interest via adaptive laboratory evolution; the final evolved strain provided a further 4.15-fold and 4.87-fold improvement to the soluble yield of the …