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Showing 1 to 20 of 68 for “"cell envelope"”.
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The Biogenesis and Homeostasis of the Shigella flexneri Cell Envelope
… of polysaccharide-based complexes on its cell surface, such as lipopolysaccharide (LPS), that facilitate host cell adhesion, and influence key immunomodulatory responses. LPS is comprised of three distinct domains including the lipid A endotoxin, a core oligosaccharide, and a highly …
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Chemical Probes and Strategies to Study Mycobacterial Cell Envelope Assembly
The cell envelope of Mycobacterium tuberculosis (Mtb) is central to its pathogenicity, immune evasion, and intrinsic drug resistance. While the importance of its glycan components is well recognized, their structural intricacies have hindered efforts to directly perturb and investigate their …
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Nonlinear electrokinetics of the bacterial cell envelope for applications in biomicrofluidics
… electrokinetic ion transport around bacterial cell envelope under the influence of externally applied electric fields. The ability to understand the physics of this ion transport has experimental applications in cell envelope phenotyping of bacteria, cell sorting, intracellular delivery of …
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A Major Cell Envelope Protein Of Escherichia Coli K12: Purification And Properties
The isolation and characterization of a major cell envelope protein from E. coli K12, the so-called "succinate eluted protein" (SEP) is reported. SEP was released by EDTA-sucrose and osmotic shock treatments, or during the formation of spheroplasts. The protein was purified on columns of …
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Uncovering Mechanisms of Cell Envelope Integrity and Nutrient Acquisition in Acinetobacter baumannii
… lacking the Mla system, we show that the cellular levels of the essential glycan carrier undecaprenyl phosphate (Und-P) are critically important for maintaining cell envelope integrity and promoting pathogenicity. In an independent study, we characterize a family of OM porins required for …
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Characterization of novel genes involved in cell envelope function in Rhizobium leguminosarum
… complex structure of the rhizobial Gram-negative cell envelope is a crucial component for both survival in the environment, as well as for establishing a successful symbiosis with its legume host. The objective of this research was to identify and characterize novel genes involved in cell envelope …
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Stress-Induced Changes in the Cell Envelope of Pseudomonas Fluorescens P-7
Made available in DSpace on 2014-12-13T19:47:44Z (GMT). No. of bitstreams: 1 7913545.pdf: 4908234 bytes, checksum: 3bdeec2a8b1a0a24362d5b750aa6e8da (MD5) Previous issue date: 1978
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Intramembrane signal transduction and cell envelope stress response in <i>Bacillus subtilis</i>
Die bakterielle Zellhülle verleiht dem Zellkörper Form und Stabilität, wirkt dem starken osmotischen Innendruck entgegen und stellt eine Permeabilitätsbarriere da. Sie wirkt als molekulares Sieb und bietet der Zelle als äußerste Schicht Schutz gegen schädliche Umwelteinflüsse. Außerdem ist die …
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Novel genes required for proper cell envelope function in the plant symbiont Rhizobium leguminosarum
The cell envelope of Gram-negative bacteria is a complex structure that is critical for facilitating interactions between bacteria and their environment. The objective of this research was to identify and characterize novel genes required for proper cell envelope development in the legume symbiont …
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A role for a predicted E. coli inner membrane lipoprotein in cell envelope integrity
… is the possession of a double-membraned cell envelope. The outer membrane provides an additional layer of protection against hydrophobic molecules including antibiotics, contributing to the multidrug resistance crisis. The Gram-negative membrane is composed of phospholipids, glycolipids, …
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Conformational Rearrangements In The Sensory Rcsf/Omp Complex Mediate Signal Transduction Across The Bacterial Cell Envelope
<p>Timely detection and repair of envelope damage are paramount for bacterial survival. The Regulator of Capsule Synthesis (Rcs) stress response is a complex signaling cascade that monitors gram-negative cell envelope integrity and can transduce the stress signals across the multilayered envelope …
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Investigating the effect of a Mycobacterium tuberculosis inhA promoter mutation in cell envelope composition and morphology
… components of mycobacterial species’ cell wall and contribute to the impermeability of cell wall by virtue of its hydrophobicity. IPMs result in a transcriptional upregulation of inhA, and mabA, which are genes involved in MA synthesis, and hemZ which is involved in heme synthesis …
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Development of Chimeric Type Iv Secretion Systems For Transfer of Heterologous Substrates Across The Gram-Negative Cell Envelope
… by translocating virulence factors across the cell envelope and into eukaryotic cells. These systems are structurally and functionally diverse, but are often compared to the archetypal VirB/VirD4 T4SS of <em>Agrobacterium tumefaciens</em>. This system is composed of the VirD4 type IV coupling …
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Changes in the Cell Envelope of Escherichia Coli Occurring Upon Variation of the Physiological State of the Cell
Made available in DSpace on 2014-12-13T20:10:17Z (GMT). No. of bitstreams: 1 7804100.pdf: 5102744 bytes, checksum: b2cdfc3bcaa9ed186ce7a38bba63bdbf (MD5) Previous issue date: 1977
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Probing the Mycobacterial Cell Envelope: CRISPR interference-mediated investigation of two essential genes in the galactan biosynthetic pathway
… the need for the identification of essential cellular pathways in mycobacteria that can be targeted for novel drug development. A key feature of Mtb that confers intrinsic tolerance to many antibiotics is its complex cell envelope. The mycobacterial cell envelope is a dynamic compartment which …
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Human papillomavirus 11 induces abnormal expression of two cornified cell envelope proteins: loricrin and the small proline rich protein 3
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Cell Envelope Modifications By Lcp Family Proteins Of Group B Streptococcus And Virulence Singaling By Peptides Of The Salivaricin Locus Of Streptococcus Pyogenes
<p>ABSTRACT</p> <p>CELL ENVELOPE MODIFICATIONS BY LCP FAMILY PROTEINS OF GROUP B STREPTOCOCCUS AND VIRULENCE SIGNALING BY PEPTIDES OF THE SALIVARICIN LOCUS OF STREPTOCOCCUS PYOGENES</p> <p>by</p> <p>HANNAH MORRISON ROWE</p> <p>December 2014</p> <p>Advisor: Dr. Melody Neely</p> <p>Major: Immunology …
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