Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"cell enrichment"”.
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A microfluidic platform for hematopoietic stem cell separation
… silicon micropost device for hematopoietic stem cell enrichment is discussed, which demonstrates how innovations in microfluidics can revolutionize current clinical therapies. Appropriate surface chemistry for robust immobilization of proteins on the surface of different materials and topography …
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CD4+ T cell response against food antigens in intestinal disease
… system, in particular antigen-specific CD4+ T cells, are thought to play a key role in this process, but the exact mechanisms leading to the development and maintenance, as well as the failure, of oral tolerance are still not fully understood. T cells that recognize one particular antigen are …
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Multi-Pronged Approach to Understanding the Toxicity Associated with CAR T-Cell Therapy
Chimeric antigen receptor (CAR) T-cell therapy has revolutionised cancer immunotherapy, providing effective treatment for previously untreatable malignancies. Its success, in treat ment of haematological cancers, is now fast-advancing to solid tumours. Though, these efforts are faced with many …
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Marker-Free Isolation and Enrichment of Rare Cell Types Including Tumor Initiating Cells through Contactless Dielectrophoresis
… (µTAS) is the separation of circulating tumor cells (CTCs) from body fluids. Cancer cells spread from the initial site of a tumor by first invading the surrounding tissue, then by entering the blood or lymph vessels, and finally by crossing the vessel wall to exit the vasculature into distal …
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Microfluidic differentiation of subpopulations of cells based on their bioelectrical signature
… important capabilities, including isolating rare cells from body fluids, such as isolating circulating tumor cells from blood or peritoneal fluid, which are not feasible or at least extremely difficult with macroscale devices. Particles experience different forces (and/or torques) when they are …