Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"cell engraftment"”.
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Evaluation of Myogenic Differentiation Potential of BMD iPSCs in vitro and the Effect of Ubiquitination Inhibitors on Dystrophin Stability in vivo
… in vitro studies include evaluation of myogenic cell proliferation and differentiation using BMD and control iPSCs to identify affected phenotypes. These were done by measuring proliferation rate, myogenic marker quantification, apoptosis and senescence assay, gene expression profiling, and cell …
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Development of a novel approach to expand umbilical cord blood-derived haematopoietic stem/progenitor cells ex vivo for clinical transplantation
… source of haematopoietic stem/progenitor cells (HSPC) for haematopoietic stem cell transplantation (HSCT). One factor limiting the wider use of UCB for transplantation is the relatively low cell dose from a UCB unit compared to bone marrow (BM) and peripheral blood (PB). To overcome this …
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Engineered Tracking and Delivery of Mesenchymal Stem Cells (MSCs)
Mesenchymal stem cells (MSCs) are tissue culture plastic adherent cells that are able to differentiate into multiple cell types, modulate the immune system, and aid in wound repair. These versatile cells are thus being investigated to treat a wide variety of different diseases such as graft vs. …
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Supramolecular Approaches to Viscoelastic Biomaterials and Their Applications
… and the shock-absorbing viscosity. The extracellular matrices (ECM), or the protein-polymer scaffolds surrounding the cells in our body, possess unique tissue-dependent viscoelasticity to protect and provide mechanical queues to the nearby cells. Viscoelasticity in polymeric hydrogels can be …
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Keratose Hydrogels Promote Vascular Smooth Muscle Differentiation from c-kit+ Human Cardiac Stem Cells: Underlying Mechanism and Therapeutic Potential
… limit this therapy. C-kit+ human cardiac stem cells (hCSCs) offers a viable alternative therapy to treat cardiovascular disease by replacing damaged cardiac tissue; however, low cell viability, low retention/engraftment, and uncontrollable in vivo differentiation after transplantation has …
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Immune Regulatory Role of Human CD141+ Dendritic Cells in Humanised Models of Alloimmunity
… model systems to explore the role of human T-cells and dendritic cells (DCs) in the regulation of human alloimmunity.<br/>The occurrence of Graft-versus-Host Disease (GvHD) is a prevalent and<br/>potentially lethal complication that develops following hematopoietic stem …
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Characterization of physicochemical properties of pan-frying bacon fat and its potential effects on breast cancer progression
… were euthanized three days after breast cancer cell engraftment to measure the acute response in the tumor microenvironment, including macrophages, neutrophils, and T cells in the pre-metastatic lung. 5) Long term effect of BF on breast cancer metastasis on BALB/c mice. The major findings of …