Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 31 for “"cell elongation"”.
-
The role of adaptor proteins Crk and CrkL in lens development
Cell shape changes and signaling pathways are essential for the development and function of the lens. During lens development proliferating epithelial cells will migrate down to the equator of the lens, differentiate into lens fiber cells, and begin to elongate along the lens capsule. The …
-
Investigating Mechanical Strain-Induced Phenotypic Changes on Prostate Cancer Cell Toward Metastasis Using a Three-Dimensional <i>In-Vitro</i> Model
As tumors enlarge and progress, tumor cells are exposed to a myriad of altered mechanical forces that could dramatically modify their behavior. The objective of this thesis is to utilize a three-dimensional (3D) <i>in-vitro</i> model to investigate mechanical strain-induced phenotypic changes in …
-
A Multi-level Mechanical Study of Hypocotyl Growth in the Dark
… Arabidopsis thaliana exhibit a striking wave of cell elongation which moves acropetally from the base to the tip of the organ over time. The combined effect of this wave of cell elongation is a pattern of organ elongation. It was aimed to understand the coordination of cellular growth and growth …
-
The Role of the Ubiquitin-Proteasome Pathway During Xylem Differentiation in <I>Zinnia elegans</I> Mesophyll Cells and <I>Arabidopsis thaliana</I>
… was conducted in <I>Zinnia</I> mesophyll cell cultures to examine potential differences between differentiating cells of tracheary element (TE) cultures and non-differentiating cells of control cultures. The pathway is highly active throughout development of differentiating TEs, a …
-
The bacterial actin-like cell division protein FtsA forms antiparallel double filaments upon binding of FtsN
Cell division is essential for the propagation of all living organisms. In the vast majority of bacteria, cell division is carried out by the divisome, a multiprotein machine spanning the cell envelope. The divisome performs membrane invagination, peptidoglycan synthesis and remodelling, and …
-
Azido Auxins: Synthesis and Use as Photoaffinity Labeling Agents
… activity in eight plant systems, and they induce cell elongation, cell division, and were polarly transported at rates comparable to indole-3-acetic acid. 4-Azido-3-acetic acid has a unique property in soybean. When soybean tissue, preincubated with 4-azidoindole-3-acetic acid, is irradiated with …
-
Hormonal regulation of phosphatidylcholine metabolism in Apium graveolens
… of phosphatidylcholine exist within the plant cell; one capable of producing signals involved in cell proliferation and the other capable of releasing signaling molecules which facilitate cell differentiation. It was the aim of this study to extend the current knowledge base through the …
-
Characterization of Arabidopsis thaliana mutants defetive in auxin metabolism
… aspects of plant growth and development such as cell elongation, cell division, apical dominance, tropisms, and fruit ripening. The most abundant naturally occurring auxin is indole-3-acetic acid (IAA). IAA is found in plants both as the free acid and in conjugated forms. It is believed that the …
-
Development of an in vitro model of contraction by fibroblasts
… conditions which promote tissue regeneration. A cell force monitor (CFM) was designed and constructed to measure quantitatively the contraction of a highly-porous, collagen-GAG matrix by fibroblasts. Using this device, contractile force, displacement, and kinetics were compared for different …
-
Studies on aluminum toxicity in an aluminum-sensitive cultivar of barley: impact on ion fluxes and calcium distribution
… roots were analyzed. Aluminum-induced changes in cell division and cell elongation were also measured in order to determine the importance of each one of these factors in root growth inhibition. These studies were correlated with measurements of the root surface area to determine the impact of …
-
Quantitative Aspects of Interface Remodeling During Germband Extension
<p>Oriented cell intercalation is an essential developmental process that shapes tissue morphologies through the directional insertion of cells between their neighbors. Intercalary behaviors in the early <em>Drosophila</em> embryo occur through a remodeling of cell topologies, with cells …
-
Characterization of Peptidoglycan, and the Enzymes that Synthesize it, in Borrelia burgdorferi and Insights into the Peptidoglycan of Other Pathogenic Borrelia
Peptidoglycan (PG) is an essential cell-wall biopolymer in virtually all bacteria. It is composed of glycan strands of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc) crosslinked by peptide chains of alternating D- and L- amino acids and diamines. PG plays an important role in 1) …
-
Characterization of two Bacillus subtilis penicillin-binding protein-coding genes, ykuA (pbpH) and yrrR (pbpI)
… (PBPs) are required in the synthesis of the cell wall of bacteria. In Bacillus subtilis, PBPs play important roles in the life cycle, including both vegetative growth and sporulation, and contribute to the formation of the different structures of vegetative cell wall and spore cortex. The B. …
-
The role of PAK6 in HGF-induced prostate cancer cell migration
Cell migration plays a significant role in carcinoma metastasis in which cancer cells move from the primary site and establish tumours at a secondary location. During tumour progression cancer cells can assume a migratory phenotype which is characterised by cell-cell dissociation and single cells …
-
Phytohormones and the Culture of Agaricus bisporus (Lange) Pilat
… agar . Phytohormones stimulated hyphal cell division and cell elongation . Increased yield was obtained by watering compost and casing soil with solutions of gibberellic acid ,α-naphthalene acetic acid and 2,4-dichlorophenoxy acetic acid ,while indole-3-acetic acid and kinetin were …
-
Characterization of the cardiogenesis of embryonic stem cells
… the leading cause of mortality worldwide. Stem cell therapy, aimed to restore contractility and proper vasculature, has gained considerable attention as an attractive therapeutic option. However, proper cell differentiation, survival and integration in an infarcted zone remain elusive. This …
-
Effect of Electrospun Mesh Diameter, Mesh Alignment, and Mechanical Stretch on Bone Marrow Stromal Cells for Ligament Tissue Engineering
… three steps: seeding bone marrow stromal cells (BMSCs) onto electrospun scaffolds, processing them into cords that allow cell infiltration, and conditioning them with uniaxial cyclic stretch. These steps were addressed in three complimentary studies to establish new methods to engineer a …
-
Investigation of Cell Morphology and Cell-Induced 3-D Matrix Reorganization
… pattern of cytoskeletal organization and cell-matrix mechanical interactions in corneal fibroblasts at the sub-cellular level. To specifically study how Rho and Rac regulate sub-cellular mechanical behavior, cells were plated inside 3-D matrices and incubated with activators and/or …
-
Investigation of mycobacterial cell wall genes and their requirement for survival in immune related stressful conditions
… Mtb's success as a pathogen is its unique cell wall and its ability to counteract various arms of the host's immune response. Understanding these survival mechanisms will help us develop new therapeutic interventions that can enhance the capacity of the immune system to kill the pathogen. A …
-
Mathematical models of hyphal tip growth
… how this process is controlled (in fungi and in cell elongation in other organisms) has been the subject of intense study over many years and has attracted considerable attention from mathematical modellers. In this thesis, we consider mathematical models of fungal tip growth that can be …
Page 1 of 2