Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"cell cycle studies"”.
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Cell cycle control governing built-in asymmetry underlying the spindle pole body duplication cycle in Saccharomyces cerevisiae
Self-renewing stem cell divisions typically couple the polarised orientation of the mitotic spindle with an invariant age-dependent pattern of centrosome inheritance. Self- renewal supports tissue homeostasis by providing, in a balanced manner, one daughter cell retaining stemness and another …
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Structural Analysis of Cycle Inhibiting Factor from Pathogenic Escherichia Coli
… arsenal of virulence factors to modulate host cell biology. Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) use a type III protein secretion system (T3SS) to inject microbial proteins into host cells. These translocated proteins possess a diverse array of biochemical …
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Folate transport and drug resistance in the African Trypanosome
… of raltitrexed toxicity. This was confirmed by cell cycle studies demonstrating cell cycle arrest in S phase which could be rescued with thymidine. Transport kinetics of folate and methotrexate were characterised and found to be competitive substrates for uptake in T. brucei. Transport of these …
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DOES CALCIUM INFLUX THROUGH T-TYPE CALCIUM CHANNEL INDUCE CARDIOMYOCYTE PROLIFERATION?
… due to its double nucleation property. Our cell cycle studies showed that there is significant difference in cell cycle distribution between α1G-/- and WT NMVMs on day seven after birth. Significantly more NMVMs are arrested in G1 phase in α1G-/-, compared to WT NMVMs. Even until 2 month …
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Telomere Dynamics and End Processing in Mammalian Cells
… end in single-stranded 3' overhangs. With each cell division, normal human cells lose a small amount of telomeric DNA due to the end-replication problem and the action of an unidentified nuclease. In order for tumor cells to divide indefinitely, they maintain telomere length by expressing the …
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Zytogenetischer und durchflusszytometrischer Nachweis von Mosaizismus bei Fanconi Anämie
Im Rahmen dieser Arbeit wurden sechs FA-Patienten und eine Patientin, bei der eine Fanconi Anämie ausgeschlossen wurde, auf das Vorhandensein eines Mosaizismus untersucht. Dabei wurde bei allen Patienten eine zytogenetische Chromosomenbruchanalyse durchgeführt und die Ergebnisse mit den Daten der …
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Global analysis of the transcriptional regulation of Sinorhizobium meliloti cell cycle progression and study of cell cycle regulation during symbiosis with Medicago sativa
The complex [alpha]-proteobacterial cell cycle regulatory network is essential not only for faithful replication and segregation of the genome, but also to coordinate unique cellular differentiation events that have evolved as adaptations to the different lifestyles of this diverse group of …
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Analysis of the S. pombe sister chromatid cohesin subunit in response to DNA damage agents during mitosis.
… intact genome perhaps defines the purpose of the cell cycle, which is a complex, organized series of events pertaining to the production of daughter cells. Every eukaryotic cell undergoes two alternative life cycles mitosis or meiosis, the first producing identical daughter cells of a diploid …