Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"cell coupling"”.
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Cell coupling and exocytosis measured in intact mouse pancreatic islets Control of {delta}-cell secretion
… measurements were applied to α-, β- and δ-cells in intact mouse pancreatic islets. The maximum rate of β-cell exocytosis during a depolarization to 0 mV was 14 granules/s, <5% of that observed in isolated β-cells. β-cell exocytosis exhibited bell-shaped voltage dependence and peaked at +20 …
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Cellular-level mechanisms of polarity and their role in plant growth
Coordinated cell polarity fields are essential for plant and animal development. Several models have been proposed for how these cell polarity fields are established. However, it remains unclear how different models are related to each other and how coordinated cell polarity fields are generated. …
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Silicium Nanodrähte für die extrazelluläre Ableitung elektrischer Aktivität
… nanowire transistors suitable for the extracellular detection of electrical activity. These sensors were characterized thoroughly and tested with HL-1 and HEK cells. The tests with HL-1 cells which are heart tumor cells spontaneously exhibiting action potentials showed that all physiological …
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Identifying factors that promote tensional homeostasis in endothelial cells
Various types of mammalian cells have an exceptional ability to adapt to externally applied mechanical stresses and strains. Because of this adaptation, cells can maintain their endogenous cytoskeletal stress at a preferred (homeostatic) state. This homeostasis of mechanical stress in cells, also …
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The Role of Gap Junctions in Congenital Diseases of the Heart
… several protein kinases that regulate myocardial cell-cell coupling. We hypothesized that mutations altering sites critical to this regulation would lead to functional or developmental abnormalities of the heart.</p> <p><strong>Methods.</strong> <em>Connexin43</em> DNA from 25 normal subjects and …
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Investigating the coordination of cardiac conduction and repolarization in ventricular myocardium
… either ephaptic (EpC) or gap junctional (GJ) coupling between cardiomyocytes can modulate cardiac conduction, repolarization, or the relationship between these two phenomena. Our lab has previously demonstrated that EpC can be modified in the ventricular epicardium using ionic and osmotic …
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Microwave accelerating structures: an innovative parallel coupled electron LINAC
… structure shunt impedance without affecting the cell to cell coupling, combining the advantages of travelling and standing wave structures. Besides in case of a breakdown only the energy stored in one cell is involved in the discharge process and not the total energy stored of the section, thus …
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Bio-interfaced Nanolaminate Surface-enhanced Raman Spectroscopy Substrates
… to simultaneously achieve high sensitivity and excellent uniformity, two previously deemed mutually exclusive properties. Two unique factors of nanolaminate SERS substrates were exploited for the improved reliability of label-free in situ classification using living cancer cells, including …
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A Discrete Monolayer Cardiac Tissue Model for Tissue Preparation Specific Modeling
… do not account for the effects of random cell shapes, cell orientations and cleft spaces inherent in these monolayers on the resulting wavefront conduction. Additionally when the continuous computer model is built to study impulse propagations, the intracellular conductivities of the model …
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Nanostrukturierte Metallelektroden zur funktionalen Kopplung an neuronale Zellen
… for signal recordings from electroactive cells. Currently, the use of planar microelectrode arrays (MEAs) is an established technique for such extracellular recordings. However, a high impedance and a low signal-to-noise ratio are challenges, which have to be addressed for the recording of …
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Messung der Zell-Zell Kopplung in Kolonkryptzellen der Ratte
Gekoppelte Zellen kommen nahezu überall im Körper vor und können mit Hilfe kommunikativer Zellkontakte eine Reihe von Funktionen erfüllen. So können die Zellen exokriner Drüsen durch die Kopplung über gap junctions als funktionelles Synzytium arbeiten. Auch die Kolonkrypte hat Eigenschaften, die …
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Transistor arrays for the direct interfacing with electrogenic cells
… gate field effect transistor (FET) for the coupling of electrogenic cells was presented. The design decoupled the transistor gate from the sensing area and arranged them one upon the other (sandwich design). Both parts were tuned individually: the transistors were optimised towards high …