Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"cd147"”.
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CD147 AS A POTENTIAL THERAPEUTIC TARGET IN GLIOBLASTOMA TREATMENT
… treatments. The human surface glycoprotein CD147, also known as basigin, is expressed at significantly higher levels in GBMs compared to non-neoplastic brain tissue. Furthermore, levels of CD147 expression correlate with brain tumor progression and show the highest expression in GBM. Here, …
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EXAMINATION OF CD133 AND CD147 AS CANCER STEM CELL MARKERS
… The cell surface glycoproteins CD133 and CD147 were examined as potential markers of cancer stem cells found in glioblastoma. Here we found evidence which shows that formation of neurospheres with U87MG glioblastoma cells may be driven by increased expression of CD147, correlated with …
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REGULATION AND PHYSIOLOGICAL ROLE OF NON-CLATHRIN ENDOCYTOSIS OF THE EPIDERMAL GROWTH FACTOR RECEPTOR
… the internalization process. In addition, CD147, a member of the immunoglobulin superfamily, was identified as a cargo co-internalizing with the EGFR in NCE vesicles. CD147 has been validated as a specific marker of NCE, and together with RTN3, represents an invaluable experimental tool for …
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Use of artificial neural network techniques to model proteomics of cellular stress
… to predict the levels of surface markers CD9 CD147 and HLA A-C based on experimental parameters of data obtained from ultra-scaled down experiments. These models where used to predict how changing the parameters would affect the density and abundance of the surface markers on the cell lines …
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DISSECTING THE MOLECULAR MECHANISMS RELATED TO THE ONSET OF NEUROLOGICAL COMPLICATIONS IN THREE CELLULAR MODELS OF SARS-COV 2 INFECTION: IPSC-DERIVED MOTO R NEURONS, IPSC-DERIVED DOPAMINERGIC NEURONS, IPSC DERIVED-HUMAN CORTICAL ORGANOIDS.
… human iPSC-derived MNs probably by binding CD147 and NRP1 receptors. Furthermore, SARS-CoV-2 infection in iPSC-MNs significantly altered the expression of genes (IL-6, ANG, S1PR1, BCL2, BAX, Casp8, HLA-A, ERAP1, CD147, MX1) associated with cell survival and metabolism, as well as antiviral …
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Discovery of prognostic biomarkers from the prostate cancer membrane proteome using bioorthogonal chemistry
… cancer cell lines revealed that Basigin (CD147) glycosylation, which showed a strong increase in Ac4ManNAz and Ac4GalNAz labelling, correlated with an increase in metastatic potential, despite its total expression decreasing across the panel of prostate cancer cell lines. In summary, we …
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Molekulare Mechanismen und Asymmetrie im Transport von Lactat
Lactat dient im menschlichen Organismus als universeller Energieträger und Signalmolekül, das zwischen lactatproduzierenden (glykolytischen) und -konsumierenden (oxidativen) Zellen und Geweben ausgetauscht wird. Dieser Austausch wird durch vier Isoformen der humanen Monocarboxylattransporter …
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Investigation of a pancreatic derived progenitor cell population for use in regenerative medicine
… but not identical. Both cell lines expressed CD147, CD44 and CD49f. Both showed low levels of CD71 expression and did not express the haematopoietic markers CD31, CD34, CD45 and c-kit. However,in contrast to the Thy1.1 positive PDPC population, the Thy1.1 negative PDPC population was positive …