Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 26 for “"caudate nucleus"”.
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Behavioral Responses to Methylphenidate: Correlations With Neuronal Activity In The Caudate Nucleus
… in DA in the motive circuit, including the caudate nucleus (CN), similar to other drugs of abuse. This study focuses on research aimed to elucidate if there are intrinsic underlying differences in the CN electrophysiological activity of animals exhibiting different chronic responses to the …
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The Neural Computations In The Caudate Nucleus For Reward-Biased Perceptual Decision-Making
… single-unit extracellular recordings in the caudate nucleus, the input station in the basal ganglia. Fitting the monkeys’ behaviors to a drift-diffusion model, we found that the monkeys used a rational heuristic to combine sensory and reward information. This heuristic is suboptimal but leads …
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Effects of frontal cortex and caudate nucleus lesions on stimulus generalization learning in rats
… median cortex (AM) described by Leonard, and the caudate nucleus (CN) on a brightness stimulus generalization task. It was hypothesized that deficits in stimulus generalization learning would be demonstrated by rats who received the AM and CN lesions, and that no deficits would be shown by FP …
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Assessment of Immune System Involvement in Tourette Syndrome
… produce IgG and IgA antibodies that bind to caudate nucleus, hippocampus, frontal cortex, cerebellum, thalamus, globus pallidus interior, exterior and putamen. Thirty- two children (14 TS, 7 family control, and 11 non-family control) and thirty-nine adults (11 TS, 14 family control, and 14 …
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Usefulness of [18F]-Deoxyglucose Positron Emission Tomography in Diagnosing the Patients with Corticobasal Degeneration
… fronto-parieto-temporal cortices, thalamus and caudate nucleus. The contralateral hemisphere to the more affected side showed decreased glucose metabolism in much wider fronto-parieto-temporal cortices. CONCLUSIONS: Quantitative FDG PET analysis showed asymmetric fronto-parieto-temporal …
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The involvement of the primate frontal cortex-basal ganglia system in arbitrary visuomotor association learning
… dorsolateral prefrontal cortex (dlPFC), caudate nucleus (Cd), frontal eye field (FEF), and the internal segment of the globus pallidus (GPi). Extracellular electrophysiological recordings were performed in awake-behaving primates performing three different learning tasks. In the different …
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Changes in Brain Functional Connectivity Following Donepezil Treatment in Alzheimer's Disease
… between the left inferior frontal gyrus and caudate nucleus. The data suggest that the drug had selective effects on executive networks of attention.
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Psychological and neural mechanisms of stay/leave decision making
… while undergoing fMRI. Increased activation in caudate nucleus was associated with stay decisions in a social rather than nonsocial context; and the dorsal anterior cingulate cortex showed differential activation as a function of stay and leave decisions and this pattern was reversed in the …
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A New Device for Stereotactic ct-Guided Biopsy of the Canine Brain: Design, Construction, and Needle Placement Accuracy
… for reasons unrelated to the brain. Deep-seated (caudate nucleus and pituitary gland) targets were identified on CT. After a 5 mm craniotomy, the biopsy needle, with CT monitoring, was progressively introduced into the target. The final needle track distance was measured on CT. The brain was …
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The role of ventrolateral prefrontal cortex in performance of spatial self-ordered response sequences in the marmoset
… glutamatergic receptors in a region of the caudate nucleus to which the vlPFC projects, but no significant effects on sequencing accuracy were observed, although there were large effects on perseverative errors in 2 out of 3 animals. The findings are discussed in Chapter 6 in terms of the …
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The Neural Computation of Trust and Reputation
… estimates of RL models within the bilateral caudate nuclei. However, our work additionally showed that this correlation was modified when reputational priors on counterparts are provided. Indeed participants continued to rely on priors even when experience shed doubt on their accuracy. …
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The effects of HIV-1 infection on subcortical brain structures in children receiving ART : a structural MRI study
… software. Structures selected included the caudate, nucleus accumbens (NA), putamen (Pu), globus pallidus (GP) and corpus callosum (CC). Four of these structures occur bilaterally. Tracing was performed in 79 subjects. Three subjects were excluded due to poor quality images or pathology; 5 …
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The neurostructural effects of prenatal exposure to methamphetamine in an infant population in the Western Cape
… exposure was associated with reduced caudate nucleus volume bilaterally, and in the right caudate following adjustment for confounders. Exposure was associated with reduced fractional anisotropy in all major white matter networks, and in individual connections within the limbic …
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The nature of habits in the nonhuman primate : the formation of sequences of eye movements and neural activity in the frontal eye field
… eye fields (FEF), prefrontal cortex (PFC), and caudate nucleus (CN) simultaneously as naïve monkeys performed a free-viewing scan task. Neural recordings began on the first day of this task where a random dot on a grid of targets was chosen to be baited with reward on every trial and the monkeys …
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Towards Gene Therapy of Parkinson’s Disease: Implantation of RUC-GDNF Secreting Mammalian Cell Lines into Rat Brain
… implanted to the anterior portion of Caudate nucleus of Sprague-Dawley rats. Cisternal CSF was collected before and up to 45 days after the cellular implantation.</p> <p>We have obtained the following results: Bioluminescence in cisternal CSF was first detected at 6 hours post-cell …
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The role of frontal-striatal circuits in instrumental behaviour
… (OFC, area 11), medial OFC (area 14) and the caudate nucleus (CN) were then compared following training, using reversible pharmacological inactivation and activation of these structures via implanted cannulae. None of the studies in the literature had examined the causal role of these brain …
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Investigation of the Shared Genetic Influences on Bipolar Disorder, Borderline Personality Disorder and Regional Brain Structures
… eight subcortical brain volumes (nucleus accumbens, amygdala, caudate nucleus, hippocampus, pallidum, putamen and thalamus) and intracranial volume (ICV) (N=27,087), and cortical surface area and thickness (N=37,479) were obtained. Pleiotropy and concordance were assessed using …
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Modelling the Neuropsychopharmacology of Obsessive-Compulsive Disorder in the Common Marmoset (Callithrix jacchus)
… critical region to be either the ventromedial caudate or the putamen. Marmosets were trained on a serial reversal task that allowed multiple acute neural manipulations, and the ventromedial caudate and putamen were then reversibly inactivated using the GABAA agonist muscimol. Results indicated …
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Effects of HIV and different anti-retroviral therapy (ART) regimes on brain structure in HIV infected children at age 7
… (LGI), and regional (corpus callosum, bilateral caudate, hippocampus, putamen, thalamus, and lateral ventricle) and global brain volumes. Vertex-wise and region of interest (ROI) comparisons were performed between and within HIV infected and uninfected children. Relationships between morphometric …
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Insecticide-Mediated Neurochemical and Behavioral Changes as Possible Predisposing Environmental Factors in Idiopathic Parkinson's Disease
Epidemiological studies implicate pesticide exposure as a possible etiologic factor in idiopathic Parkinson's Disease, which results from degeneration of nigrostriatal neurons, along with reduced levels of the neurotransmitter, dopamine. Behavioral and neurochemical analyses in C57BL6 mice were …
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