Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"case-cohort"”.
-
Beyond Parameter Estimation: Analysis of the Case-Cohort Design in Cox Models
Cohort studies allow for powerful analysis, but an exposure may be too expensive to measure in the whole cohort. The case-cohort design measures covariates in a random sample (subcohort) of the full cohort, as well as in all cases that emerge, regardless of their initial presence in the subcohort. …
-
Modifications and extensions of the logistic regression and Cox model
… as a set of covariates. However, epidemiologic cohort studies are quite expensive regarding data management since following up a large number of individuals takes long time. Therefore, the case-cohort design is applied to reduce cost and time for data collection. The case-cohort sampling …
-
Genetic epidemiology of markers of genomic ageing
… (MR), and prospective observational case-cohort analysis methods were used to (1) identify novel genetic determinants of LTL, (2) investigate causal associations of genetic differences in LTL with disease, (3) review the evidence on and assess the feasibility of studying longitudinal …
-
Contributions to Semiparametric Inference to Biased-Sampled and Financial Data
… functions which are readily available in most cases. Return series from the market are used for estimation. In addition to the return series, there are many derivatives actively traded in the market whose prices also contain information about parameters of the underlying process. This …
-
Weighting and moment conditions in Bayesian inference
… the unit sampling probabilities. It is often the case, however, that the sampling mechanism is unknown. Methods that use estimated weights include so-called doubly robust estimators, which have become popular in causal inference. There is a lack of consensus regarding the role of probability …
-
The interplay between genes and dietary factors in the aetiology of Type 2 Diabetes Mellitus
… in a large European multi-centre prospective T2D case-cohort study called EPIC-InterAct. We concluded that the heterogeneity between our results and those published could be explained by methodological differences in dietary measurement, population under study, study design and analysis but also …
-
Linking whole-grain bread, coffee, and red meat to the risk of type 2 diabetes
… of developing type 2 diabetes in prospective cohort studies, but potentially underlying biological mechanisms are not well understood. Metabolomics profiles were shown to be sensitive to these dietary exposures, and at the same time to be informative with respect to the risk of type 2 …
-
Early Pregnancy Maternal Vitamin D Concentrations in Relation to Gestational Diabetes Mellitus, Mood or Anxiety Disorders, and Preeclampsia
… these associations is unknown. Methods: In a case-cohort study nested within a prospective cohort, we examined these associations. Analytic samples included: 135 GDM cases and a randomly selected sub-cohort of 517; 148 MAD cases diagnosed before or during pregnancy and a sub-cohort of 554 (and …
-
Application of biomarker-based assessment of dietary patterns to nutritional epidemiology: observational and interventional investigations with a focus on the Mediterranean diet and type 2 diabetes
… pattern. Chapter 3: I used the EPIC-InterAct case-cohort study which measured nutritional biomarkers at scale (~13,000 subcohort participants and ~9,000 incident type 2 diabetes cases) to evaluate the utility of combining them into biomarker scores predictive of adherence to dietary patterns, …