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Showing 1 to 5 of 5 for “"carvedilol"”.
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The development, validation, and evaluation of quantitative assays for determining adherence of heart failure patients to carvedilol, enalapril and perindopril
… multiplex assays were developed to quantify carvedilol, enalaprilat and perindoprilat in dried blood spots (DBS) and correlated with plasma. Carvedilol, enalapril and perindopril are medications commonly used to treat HF, with enalaprilat and perindoprilat being the active metabolites of …
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Determining the Effects and Signaling Properties of β-Blockers in House Dust Mite-Driven Murine Models of Asthma
… However, not all β-blockers seemed to work as carvedilol and propranolol did not reduce the asthma phenotype in mice. Further studies in our laboratory suggested a correlation between the ability of β-blockers to reduce the asthma phenotype in murine models and their inhibition of the β2AR- …
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Apparent dissolution rate enhancement of poorly-water soluble drugs by adsorption technique
… poor-water soluble model drugs, ibuprofen and carvedilol were used. Methanol, DMF, DMSO and PEG400 were used as solvents and microcrystalline cellulose was used as an adsorbent. Pure model drugs, physical mixtures and prepared composites were characterized by using FTIR, DSC, XRD and …
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Evidenz-basierte Pharmakotherapie der Herzinsuffizienz an der stationär-ambulanten Schnittstelle
… Langzeiteffekt (Metoprolol, Bisoprolol, Carvedilol, 64,3% vs. 89.0%). Auch Aldosteronantagonisten wurden in der Klinik häufiger verabreicht als nach Entlassung (38,5% vs. 33,8%). Die Verordnung der Aldosteronantagonisten erfolgte sowohl in der Klinik, als auch bei den Hausärzten …
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Phosphorylation Bar Codes Induce Distinct Conformations and Functionalities of beta-Arrestin
… or a beta-arrestin "biased" agonist, carvedilol, in the presence of a full complement of GRKs or when individual GRKs (2 or 6) were depleted by siRNA. We demonstrate that at least thirteen sites on the beta2AR show changes in phosphorylation in response to the agonist isoproterenol. Of …