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Showing 1 to 6 of 6 for “"carotenoid cleavage"”.
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Directed evolution of Arabidopsis thaliana carotenoid cleavage dioxygenase 1
Arabidopsis thaliana Carotenoid Cleavage Dioxygenase 1 (AtCCD1) is the role model for CCDs, a class of enzymes that cleave highly specific C=C double bonds in carotenoids and apo-carotenoids. CCD1s cleave carotenoids symmetrically and regio-selective at the 9-10 and 9’-10’ position. The active site …
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Genotype effects impact lipids and organ weights in female mice lacking carotenoid cleavage enzymes
Carotenoids are very abundant in nature and their consumption has numerous positive health outcomes. There are two known enzymes that are responsible for cleaving carotenoids in to their metabolites. β-carotene is cleaved by carotenoid-15,15'-oxygenase (CMO-I), to eventually form …
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The Role of Carotenoid Cleavage Dioxygenase 4 in Flower Color of the Allopolyploid Brassica napus
… to examine subgenomic interactions. <em>CAROTENOID CLEAVAGE DIOXYGENASE</em> 4 (<em>CCD4</em>)<em> </em>is known to play a major role in determining flower color phenotype of carotenoid-synthesizing angiosperms. Here, we investigate the genetic and epigenetic role of <em>CCD4 …
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Insight Into the Metabolism of Lycopene: Focus on Androgen -Dependent Tissues
… the other analyzed tissues. Moreover, modulated carotenoid cleavage enzyme(s) expression in the adrenal, prostate and kidney suggested that the accumulated lyc metabolites in these tissues be involved in the observed transcriptional changes. In essence, lyc has previously been reported to improve …
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Genetic dissection of carotenoid concentration and compositional traits in maize grain
Carotenoid compounds are derivatives of a well described secondary metabolic pathway in plants, participating in a diverse array of physiological functions, and are nutritionally valued vitamin precursors in the human diet. With the goal of enhancing the quantity (concentration) and quality …
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Dietary tomato carotenoids and β-carotene-15,15'- dioxygenase (Bco1) genotype alter androgen metabolism, lipid metabolism, and prostate cancer progression in mice
… (BCO1) cleaves dietary carotenoids at the central 15,15' double bond, most notably acting on β-carotene to yield retinal. Much work has gone into the description of enzymatic carotenoid cleavage activities of the enzyme, but although pleiotropic effects of Bco1 loss on …