Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"carnosic acid"”.
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Carnosic acid against insulin resistance and obesity. Investigating its effects on adipocytes.
… of the most abundant polyphenols in rosemary is carnosic acid, a compound exhibiting potent antioxidant, antiinflammatory, anticancer, and anti-hyperglycemic properties. Furthermore, based on the limited evidence available, it appears as though carnosic acid may have anti-obesity and antidiabetic …
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Dissecting the anti-allergic potential of carnosic acid during IgE and IL-33-mediated mast cell activation
… alleviate the severity of the allergy epidemic. Carnosic acid (CA), a major polyphenolic constituent of the Lamiaceae family herbs has been shown to exhibit potent anti-inflammatory effects on other cellular models, but it’s role as a potential modulator of mast cell activation is currently …
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Nose to Brain Delivery of Therapeutic Agents
… factor (BDNF)], neurotrophinogenic agents (ex: carnosic acid) and antibiotics (ex: cefotaxime) to brain via nose-brain pathway using chitosan as barrier modulating agent was investigated. In vitro permeation studies of fluorescein isothiocyanate dextran (FD40k) across bovine olfactory mucosa …
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Investigation of the Biological Effects of Rosemary (Rosmarinus Officinalis L.) Extract in Human Lung Cancer Cells
… effects of RE and its polyphenolic constituents carnosic acid (CA) and rosmarinic acid (RA) in lung cancer. The present study shows RE, CA and RA inhibit lung cancer cell proliferation and survival in various NSCLC cell lines and that CA and RA interact synergistically to inhibit cell …
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Investigating the Biological Effects of Rosemary (Rosmarinus officinalis L.) Extract on Skeletal Muscle Glucose Uptake
… RE to levels similar to insulin and metformin. Carnosic acid (CA) and rosmarinic acid (RA), major polyphenols found in RE, increased GU. RE, CA, and RA significantly increased AMPK phosphorylation and their effects on GU was reduced by an AMPK inhibitor. Our study is the first to show a direct …
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Inhibition of Free fatty acid-Induced Insulin Resistance by Rosemary Extract: Investigation of the Mechanisms Involved
Excess of plasma free fatty acids (FFA) are highly associated with insulin resistance and are a major risk factor for the development of type 2 diabetes mellitus. This thesis investigates the effect of rosemary extract and rosemary extract polyphenols carnosic acid (CA), rosmarinic acid (RA) and …
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Testing the Anti-Inflammatory Effects of Dietary Phytochemicals in Intestinal Inflammation Models
… and anti-inflammatory phytochemicals. Carnosic acid (CA) and carnosol (CL) are the most abundant diterpenes in rosemary, however less abundant diterpenes are understudied. Fractions that excluded CA and CL from the diterpene-rich oil-soluble rosemary extract, VivOX® 40, activated the …
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INHIBITED MINERALIZATION IN OSTEOBLASTS CULTURED UNDER VARIED SIMULATED PARTIAL GRAVITY CONDITIONS AND THE USE OF PHYTONUTRIENTS FOR MITIGATING THE EFFECTS OF REDUCED GRAVITY
… was made into the effectiveness of curcumin and carnosic acid, two nutritional antioxidants with pro-osteogenic properties, contrasted with the trace element zinc, as potential alimentary supplements that may mitigate or alleviate the deleterious effects of microgravity. Results showed that …