Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"cargo translocation"”.
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Conformational Dynamics of the Nuclear Pore Complex Studied With Coarse-Grained Modelling and Polarized Light Microscopy
… in vivo. Although various models for how cargo translocates the NPC have been proposed, the mechanism remains unclear. However, most models for transport propose a crucial role for the phenylalanine-glycine nucleoporins (FG-Nups). I constructed a coarse-grained model to investigate the …
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Examining the Regulation of Cell Division by the Spindle Assembly Checkpoint
… and SAC silencing, as well as a variety of cargo-translocation roles in interphase. I examine the effects of the small molecule "ciliobrevin" in mitotic cells and help validate it as the first specific dynein inhibitor. Although I determine that its effects on the microtubule spindle will …