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Showing 1 to 5 of 5 for “"cardiovascular progenitor cells"”.
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Molecular Mechanisms That Govern Human Cardiac Stem Cell Age Disparity
<p>Transplantation of adult endogenous cardiovascular progenitor cells for heart repair results in some clinical benefit, however these stem cells lack the regenerative capacity unique to neonatal cardiovascular stem cells. The goal of this work was to identify mechanisms that contribute to the …
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A Novel Population of Cardiovascular Progenitors Persist in Neonates as Mesendodermal Cells
<p>The rise in mortality due to cardiovascular disease has increased the need to develop an efficient regenerative therapeutic for heart failure. Numerous cell-based therapies have been investigated for myocardial regeneration; however, an optimal progenitor has yet to be discovered. Identifying a …
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Microgravity Exerts an Age-Dependent Effect on Cardiovascular Progenitor Cell Development
… is the promotion of the efficacious use of stem cells in therapies on Earth. For this reason, neonatal and adult human cardiovascular progenitor cells (CPCs) were cultured aboard the International Space Station (ISS). Subsequently, we assessed the effects of mechanical unloading on developmental …
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PRIMING CARDIOVASCULAR STEM CELLS FOR TRANSPLANTATION USING SHORT-TERM HYPOXIA
… However, a majority of those suffering from cardiovascular diseases are older adults whose autologous cells no longer possess optimum functional capacity. Additional work is needed to identify the optimal cell types or conditions that will promote cardiovascular regeneration across all age …
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Differentiation of Flk-1 positive multipotent adult germline stem cells into endothelial cells in vitro and in vivo
Multipotente adulte Keimbahnstammzellen (maGSCs) stellen eine mögliche Quelle für stammzellbasierte Therapien ohne immunologische Abstoßung und ethische Probleme dar. In der vorliegenden Dissertation werden die Herstellung und Expansion Fetale Leberkinase-1 (Flk-1) positiver kardiovaskulärer …