Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"cardiovascular homeostasis"”.
-
Effect of the Pdgfbʳᵉᵗ mutation on cardiovascular homeostasis
… / PDGFRβ signalling is a key regulator of the cardiovascular system in development, health, and disease. During angiogenesis PDGFB regulates pericyte migration and proliferation during development and in tissue repair. Pericytes confer vessel stability, maintain vessel integrity, and control …
-
Characterization of Endothelial Nitric Oxide Synthase Serine-600 Phosphorylation
… functions that range from maintaining cardiovascular homeostasis to neurotransmission. The function of NO greatly depends on the concentration and is cell type specific. eNOS is the most regulated of the three NOS isoforms and the mechanisms of regulation can be through protein-protein …
-
Investigating the role of the Renin Angiotensin System in cancer
… link with metabolic diseases, including that of cardiovascular disease, diabetes, amongst others, where common sets of genes show similar gene expression. There is thus interest to investigate current therapies for metabolic diseases as possible anti-cancer agents. The renin-angiotensin system …
-
Role of kinins in mediating vascular function in healthy pregnancy and pre-eclampsia
… endothelium that contribute to the regulation of cardiovascular homeostasis by inducing vasodilation, fibrinolysis and angiogenesis. Given that pre-eclampsia is associated with reduced endotheliumdependent relaxation, coagulation abnormalities and an angiogenic imbalance, it was hypothesised that …
-
EFFECTS OF ACUTE NORMOBARIC HYPOXIA DURING EXERCISE AND CONCURRENT MENTAL STRESS ON THE CARDIOVASCULAR SYSTEM IN HEALTHY ATHLETES
… as physiological stressors that challenge cardiovascular homeostasis through mechanisms orchestrated by medullary cardiovascular control centers. During physical exertion, the activation of the “exercise pressor reflex” facilitates systemic adjustments to preserve perfusion of vital organs …
-
Dietary Intake and Bio-activation of Nitrite and Nitrate in Newborn Infants
… nitrate and nitrite play an important role in cardiovascular and gastrointestinal homeostasis through conversion back into NO via a physiological system involving enterosalivary recirculation, bacterial nitrate reductases, and enzyme-catalyzed or acidic reduction of nitrite to NO. The diet is a …
-
Studies of aldosterone renin ratio and genetic variation at the CYP11B1/CYP11B2 locus in human essential hypertension
… because it represents a major risk factor for cardiovascular disease. Both genetic and environmental factors contribute to the regulation of blood pressure, thus making the study of hypertension difficult and complex. Over recent years, with the advent of new molecular technologies, there has …