Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"cardiometabolic traits"”.
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Genetic studies of cardiometabolic traits
… and type 2 diabetes (T2D). Together, these cardiometabolic traits and diseases, have contributed to the increased burden of cardiovascular disease, the leading cause of death in Western societies. Complex traits and diseases, such as cardiometabolic traits, arise as a result of the …
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EXAMINING THE CONTRIBUTION OF GENETIC VARIANTS TO CARDIOMETABOLIC TRAITS
… disease (CVD). There are many risk factors for cardiometabolic disease (the global risk of developing T2D and/or CVD). These include altered glucose homeostasis, abnormal lipid metabolism, and increased inflammation, as well as the environmental and genetic components underlying these …
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Exploring Multivariate Gene-Environment Interactions: Models And Applications
… apply the StructLMM interaction test to multiple cardiometabolic traits using the UK Biobank data, facilitating exploration of shared G$\times$E \newline architecture. Additionally, I provide preliminary estimates of the amount of \newline phenotypic variation that can be explained by G$\times$E …
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Effects of blood donation and iron homeostasis on medium and long term cardiometabolic outcomes
… of blood donation and iron homeostasis on cardiometabolic outcomes remains unclear. Objectives. This thesis aims to reliably characterise the relevance of blood donation and iron homeostasis on cardiometabolic outcomes while overcoming some limitations of previous studies. Data sources (i) …
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Genetic Determinants of Obesity in Relation to Diet, Weight Gain and Mortality
… IV) and tried to dissect the causality between cardiometabolic traits and mortality (paper V). The work in this thesis was conducted using data from the population based prospective Malmö Diet and Cancer Study (MDCS; N= ~30,000) and the Gene-Lifestyle interactions And Complex traits Involved in …