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Showing 1 to 7 of 7 for “"cardiac neural crest"”.
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Effects of Homocysteine on Cardiac Neural Crest Cell Formation
… of congenital detects, many of which resemble neural crest (NC) cell ablation. However, the etiological mechanism is not known. The purpose of this study was to determine if Hcys altered the number and/or the proliferation of NC cells or their progenitors /?? Uw. Hcys was experimentally …
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The Role of Sonic Hedgehog in Outflow Tract Development
… the heart are the secondary heart field and the cardiac neural crest. These two populations are responsible for providing the myocardium that supports the outflow tract valves, the smooth muscle that surrounds these valves and the outflow vessels themselves, and the septum that divides the …
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Analysis of Band 4.1B In Integrin-Mediated Cell Adhesion and Signaling
… and Band 4.1B genes resulted in impaired cardiac morphogenesis, leading to embryonic lethality by E11.5. These embryos displayed malformation of the outflow tract that was likely linked to abnormal regulation of cardiac neural crest migration. These data indicate the importance of …
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Yap and Taz Are Required For Neural Crest-Derived Cardiovascular Development
… and are a leading cause of early infant death. Cardiac neural crest cells (NCCs) are a migratory and multipotent cell population known to aid in the development of the cardiac outflow tract (OFT), valves, and interventricular septum, during embryogenesis. <em>Yap </em>and <em>Taz </em>are …
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The Chemokine Receptor CXCR7 Functions in Endocardial-Derived Cells to Regulate Cardiac Valve Remodeling
Cardiac disease is the number one killer in developed countries and congenital heart diseases are the most common birth defects worldwide. The heart supplies nutrients and oxygen to the entire body, therefore the proper development and function of the heart is essential for survival of an organism. …
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Transcriptional and Translational Regulation of Cardiac Progenitors in the Mouse and Zebrafish
… the heart is the first organ to function and cardiac progenitors are among the first cell lineages to be established. Transcriptional networks control the specification of cardiac progenitors, however, it is not fully understood how some transcription factors function in particular cardiac …
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Anteriore Musterbildung im Wirbeltierembryo - Die Induktion von Vorderhirn und Herz
… der Maus als Quelle für Signale, die eine Neuralplatte mit anteriorer Identität induzieren können, untersucht. Die Initiierung der Vorderhirnanlage beruht im Säuger auf Signalen aus dem anterioren, primitiven Endoderm. Dennoch sind, wie in dieser Arbeit gezeigt werden konnte, Signale aus …