Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 81 for “"cardiac muscle"”.
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Myosin and electrophysiological heterogeneity in cardiac muscle
Abstract available p. v-vii
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Contribution of troponin-I to the regulation of cardiac muscle
… which along with tropomyosin regulates striated muscle contraction. The cardiac isoform of TnI (cTnI) has a ~30 residue N-terminal extension, which contains two serines (Ser22/23) that become phosphorylated by protein kinase A upon \(\beta\)-adrenergic stimulation. However, the function of the …
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Palmitoylation and Glutathionylation of Key Sarcolemmal Signalling Proteins in Cardiac Muscle
… many physiological processes involved in cardiac homeostasis. However, only a handful of these proteins have been identified, therefore using isolated Adult Rat Ventricular Myocytes (ARVM) under physiological conditions, glutathionylated proteins were identified using LC-MS/MS and cross …
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MEF2-regulated Gtl2-Dio3 noncoding RNAs in cardiac muscle and disease
… factor is a central regulator of skeletal and cardiac muscle development. Recently, we showed that MEF2A regulates skeletal muscle regeneration through direct regulation of the Gtl2-Dio3 microRNA mega-cluster. In addition to their expression in skeletal muscle, temporal expression analysis of …
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The extent of cardiac muscle in the great vessels of the dog
Thesis (M.S.)--Michigan State University of Agriculture and Applied Science. Dept. of Anatomy, 1960
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Scalable production of cellular aggregates for the differentiation of embryonic stem cells into cardiac muscle
Embryonic stem (ES) cells have the potential to treat many diseases, such as heart disease, diabetes, and Parkinson's disease. However, large numbers of desired differentiated or progenitor cells must be generated from ES cells for many regenerative medicine applications to be successful. Current …
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In vitro exploration of interactions between junctin and the Ryanodine receptor from skeletal and cardiac muscle
Muscle contraction is dependent on a large Ca2+ release from its intracellular Ca2+ store, the Sarcoplasmic Reticulum (SR), through Ryanodine receptor Ca2+ release channels (RyRs). In the resting state, striated muscle requires a tight control of Ca2+ release through RyRs. Another SR bound protein, …
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In vitro exploration of interactions between junctin and the Ryanodine receptor from skeletal and cardiac muscle
Muscle contraction is dependent on a large Ca2+ release from its intracellular Ca2+ store, the Sarcoplasmic Reticulum (SR), through Ryanodine receptor Ca2+ release channels (RyRs). In the resting state, striated muscle requires a tight control of Ca2+ release through RyRs. Another SR bound protein, …
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Influence of biological sex and thyroid hormone on skeletal and cardiac muscle metabolism in heat-stressed pigs
… temperatures caused by climate change. Skeletal muscle, which is the main source of income for the meat industry, is particularly sensitive to HS. Lean tissue accretion declines during HS, in part because of inefficient metabolism and altered metabolic flexibility. The first study examined …
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Identification and Characterization of the Role of REEP5 in Sarco-Endoplasmic Reticulum Formation, Maintenance, and Function in Cardiac Muscle
… that are conserved among eukaryotic species, cardiac-enriched, and have not been previously linked to a cardiac phenotype. These poorly annotated cardiac-enriched membrane proteins represent excellent candidates in follow-up studies aimed at elucidating the underlying molecular mechanisms of …
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The effects of force on actin-myosin ATPase activity
When skeletal and cardiac muscle contract they generate movement through the actin-myosin ATPase reaction. However, the chemical reaction underlying movement remains unclear. Specifically, little is known about how the forces generated by muscle influence the chemistry of the force-generating …
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Gene Regulatory Networks in Striated Muscle Pathologies
The striated musculature, comprised of skeletal muscle and cardiac muscle tissues, is essential for vertebrate life. Skeletal muscles are composed of bundles of long and parallel multinucleated myofibers that constitute approximately 40% of the human body mass. The cardiac muscle is much smaller …
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A theoretical study of left ventricular and heart muscle dynamics
… synthesised from anatomical data concerning the cardiac muscle fibre structure of the wall. Its mechanical and dynamical properties are then, as in the physiological situation, dependent on those of the muscle fibre. These fibre properties have also been fully investigated and a simple new model …
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