Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"cardiac MRI"”.
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Computer Aided Analysis of Late Gadolinium Enhanced Cardiac MRI
… and therapy planning. Among various clinical cardiac scans, late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) imaging can directly visualize and thus discriminate non-viable myocardium (i.e., infarcts) from normal myocardium via hyper-enhanced intensities. Since manual analysis …
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Shape and Function Analysis in Large Cardiac MRI Datasets
… resonance imaging, the development of specific cardiac sequences has allowed radiologists to learn the anatomy and function of the heart in a new noninvasive fashion. The work presented in this thesis centres on the problem of comparing the mathematical models derived from these images. This is …
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Artifact reduction in cardiac MRI in patients with varying heart rate
Late enhancement MRI is an important tool in assessing various cardiomyopathies and risks associated with them. The diagnosis, however, is dependent on the image quality, which can be reduced by numerous factors, including arrhythmia and varying heart rate. This project analyses the inversion …
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Uncertainty-aware fusion of foundation and task-specific models for cardiac MRI segmentation
… anatomical precision of task-specific models for cardiac MRI segmentation. The approach combines Dempster-Shafer Theory (DST) with an entropy-guided fallback mechanism to perform voxel-wise fusion of calibrated probability maps. DST fusion is applied in regions of agreement, while high-conflict …
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Cardiac MRI Data Segmentation Using the Partial Differential Equation of Allen–Cahn Type
… of the left heart ventricle from the cardiac MRI images with the subsequent interpretation of its dynamics.
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RANDOMIZED COST COMPARISON OF CARDIAC MRI USE IN EMERGENCY DEPARTMENT PATIENTS WITH CHEST PAIN
… diagnostic strategies: an observation unit (OU) cardiac MRI (CMR) strategy and inpatient care. Methods A single center clinical trial randomized 110 patients with intermediate-risk chest pain (TIMI ≥2 or clinical impression) to OU CMR (OU care, serial cardiac markers and stress CMR) or inpatient …
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A control system approach to subject specific prospective respiratory motion correction in cardiac MRI
… of the heart is a problem for high-resolution cardiac MRI. Diaphragmatic navigator gating with a 5mm acceptance window is most commonly used to address this but has an inherently low respiratory efficiency that is further compromised by respiratory drift. A novel method is presented that uses …
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Single magnetic resonance image super-resolution using generative adversarial network
… image super-resolution problem of the brain and cardiac MRI datasets. To increase the spatial resolution of these medical images, we have adapted a Generative Adversarial Network (GAN) model where the generator has a DenseNet type structure and the discriminator is based on the U-Net model. We …
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Towards automating cine DENSE MRI image analysis : segmentation, tissue tracking and strain computation
… past two decades, magnetic resonance imaging (MRI) has developed into a powerful imaging tool for the heart. Imaging cardiac morphology is now commonplace in clinical practice, and a plethora of quantitative techniques have also arisen on the research front. Myocardial tagging is an established …
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MOLECULAR DISSECTION OF CARDIOMYOPATHY
… and dilated cardiomyopathy (DCM) are inherited cardiac conditions with marked genetic heterogeneity. The genetic aetiology of HCM and DCM in Singapore and European was broadly similar but Singapore Chinese HCM patients frequently have fewer clinically actionable disease variants, overall. Two …
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Temporal registration for MRI time series
… method to correct for motion and deformations in MRI time series. We make a Markov assumption on the nature of deformations to take advantage of the temporal smoothness in the image data. Forward message passing in the corresponding hidden Markov model (HMM) yields an estimation algorithm that …
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Comparative Analysis of Pressure Mapping Methods in Repaired Tetralogy of Fallot: Four-Dimensional Blood Flow Hemodynamics Assessment and Development of a Novel Pressure Mapping Tool
… 4D-flow magnetic resonance imaging (4D-flow MRI), has been applied to identify abnormal heart hemodynamics in CHD. Hence, the aim of this research was to compare pressure drop and relative pressures between patients with repaired TOF (rTOF) and healthy volunteers. An in vitro validation was …
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Imaging Post-Infarct Myocardial Inflammation with ⁶⁸Ga-DOTATATE PET/MRI and insights into COVID-19 associated myocardial injury
… infarction (MI) may contribute to adverse cardiac remodelling. <sup>68</sup>Ga-DOTATATE is a PET radiotracer with high affinity for somatostatin receptor subtype 2 (SST2), which has been shown to be up-regulated in pro-inflammatory macrophages. Aims: To investigate the role of hybrid …
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CARDIOVASCULAR RESPONSES TO ACUTE EXERCISE IN ANTHRACYCLINE TREATED CANCER SURVIVORS AND HEALTHY CONTROLS
… comparison group. Each participant had a resting cardiac MRI (CMR) and then performed a maximal exercise test on a treadmill to obtain peak oxygen consumption (VO2 peak) and heart rate (HR). Immediately (<30 sec) following the exercise test, the participant was redirected into the scanner for …
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Kinematic Characterization of Left Ventricular Chamber Stiffness and Relaxation
… using both non-invasive (echocardiography, cardiac MRI) and invasive (simultaneous catheterization-echocardiography) methods. Our group developed and validated the Parametrized Diastolic Filling (PDF) formalism which is motivated by basic physiologic principles (LV is a mechanical suction …
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Discrete Optimization in Early Vision - Model Tractability Versus Fidelity
… by three applications to early vision problems: cardiac MRI segmentation, image registration, and cell classification.
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Four-Dimensional Cardiac Magnetic Resonance Analysis in Patients with Atrial Fibrillation
Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by disorganized electrical activity leading to irregular contractions and impaired cardiac output. AF significantly elevates the risk of thromboembolic stroke, primarily due to thrombus formation in the left atrium (LA) and left …
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The role of pulmonary arterial stiffness in right ventricular remodelling in COPD
… heart catheterization, however recent advance in MRI are yielding new opportunities to undertake this assessment noninvasively. Pulse wave velocity is one of the most commonly used techniques in the systemic circulation but has been poorly explored in the pulmonary circulation. This thesis was …
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MATRIX METALLOPROTEINASES AND LEFT VENTRICLE MASS AND FUNCTION
… Our objective was to establish a biomarker of cardiac extra cellular matrix (ECM) degradation that can be used to better identify asymptomatic individuals with increased LV mass, impaired LV volumes and functions and those at risk for progression to clinical heart failure.
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SEX DIFFERENCES IN THE RELATIONSHIP OF POLYUNSATURATED FATTY ACIDS AND NONINVASIVE IMAGING MEASURES OF SUBCLINICAL CARDIOVASCULAR DISEASE
Background: The association between plasma phospholipid omega-6 levels and cardiovascular disease (CVD) morbidity and mortality is unclear, and discrepancy remains concerning the cardiovascular benefit of the omega-3 fatty acid alpha-linolenic acid (ALA).
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