Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"carboxyltransferase"”.
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A four-cysteine zinc finger in carboxyltransferase structurally links the functions of enzymatic activity and negative feedback regulation of translation
… a biotin carboxyl carrier protein, and a carboxyltransferase. The carboxyltransferase enzyme has an α2β2 heterotetrameric quaternary arrangement. The crystal structure of the β subunit revealed a zinc-binding domain, a feature common among nucleic acid-binding proteins. Carboxyltransferase …
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Studies of Acetyl-Coa Carboxylase From Escherichia Coli
… assignments for the two subunits in the carboxyltransferase complex have been given. The alpha subunit (AccA) appears to have a structural role in the total ACC complex while the beta subunit (AccD) could contain the carboxyltransferase active site. The above conclusions are based on …
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Design, Synthesis, and Antibacterial Properties of Dual-Ligand Inhibitors of Acetyl-CoA Carboxylase and Mechanism of Action for the Antibacterial Agent Moiramide B
… biotin carboxyl carrier protein, and carboxyltransferase. The research presented in this dissertation describes dual-ligand inhibitors incorporating selective inhibitors against biotin carboxylase and carboxyltransferase that were synthesized by covalently attaching them with saturated …
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The role of cysteine 230 and lysine 238 of biotin carboxylase in the deprotonation of biotin and synthesis of bisubstrate analogy inhibitor of carboxyltransferase
… a biotin carboxyl carrier protein, and a carboxyltransferase protein. This enzyme uses the cofactor biotin as a carboxyl carrier. In order for the carboxylation of biotin to occur, biotin must be deprotonated at its N-1 position. It has been proposed that the active site residues cysteine …
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Studies of Escherichia coli Acetyl-CoA carboxylase
… separate components: biotin carboxylase (BC), carboxyltransferase (CT), and biotin carboxyl carrier protein (BCCP). BC carries out the first half of the ACC reaction where it catalyzes the carboxylation of a biotin moiety covalently linked to the BCCP. BC exists as a dimer but mutated versions …
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Autotrophe CO2-Fixierung in thermophilen Mikroorganismen
… AccB, Biotin-Carrier-Protein AccC, Carboxyltransferase PccB) aufgebaut und katalysiert beide Carboxylierungsreaktionen mit der gleichen Rate. Im Gegensatz zu den Carboxylasen der meisten anderen Organismen ist das Enzym aus M. sedula stabil und konnte als Holoenzym gereinigt werden. …
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Discovery and characterization of regulatory mechanisms affecting the heteromeric acetyl-coenzyme a carboxylase in Arabidopsis
… carrier protein (BCCP), and alpha- and beta-carboxyltransferase (CT). Heteromeric ACCase is present in prokaryotes and the plastids of most plants, and has been a focus of biotechnology research due to its prominent role in FAS. Many different regulatory mechanisms have been identified in …