Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 76 for “"carboxylation"”.
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Iridium (III) photosensitisers for photoredox catalysed carboxylation reactions of ketimines
… the visible light mediated photoredox catalysed carboxylation reaction of ketimines using CO2, affording unnatural amino acids. This known reaction was selected as an ideal proof-of-concept reaction, due to the green nature of the reaction (with respect to Green Chemistry principles) and the …
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Reductive Carboxylation Is a Novel Pathway of Glutamine Metabolism That Supports the Growth of Tumor Cells with Metabolic Defects
… tricarboxylic acid cycle, termed reductive carboxylation; providing a plausible mechanism for how cancer cells with mitochondrial defects generate biosynthetic precursors required for growth. To gain mechanistic insight into how this unusual pathway was regulated I carried out a targeted …
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Studies on some enzymatic properties of mitochondrial propionyl carboxylase
… from bovine liver mitochondria catalyzes the carboxylation of 992 micromoles of propionyl-CoA per hour per milligram of protein. Relative carboxylation rates for acetyl-, propionyl-, butyryl-, and valeryl-CoA remain constant during purification. The carboxylase is inhibited by PCMB, …
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The eco-physiology of New Zealand forest lichens with special reference to carbon dioxide exchange
… into two components; (a) the sensitivity of the carboxylation system and (b), the rate of CO₂ evolution in the light at zero CO₂. Of the lichen species studied all but P. billardierii had a carboxylation sensitivity typical of the values expected in C3 plants. P. billardierii had an unusually low …
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Variation in the Substrate Specificity of Ribulose-1,5-Bisphosphate Carboxylase/oxygenase
… in order to identify conditions which alter the carboxylation and oxygenation functions differentially. Primary emphasis was on the CO(,2)/O(,2) specificity factor (SF = V(,c)K(,o)/V(,o)K(,c)) which was determined by measuring the rates of carboxylation and oxygenation of RuBp at known …
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Functional discovery and promiscuity in the RuBisCO superfamily
… carboxylase/oxygenase (RuBisCO) catalyzes the carboxylation of D-ribulose 1,5-bisphosphate to yield two molecules of 3-phosphoglycerate. Currently, there are four forms of RuBisCO, three of which catalyze the canonical carboxylation reaction. Form IV RuBisCOs (also known as RuBisCO-like …
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The purification and characterization of phosphoenolpyruvate carboxykinase
… the inosine diphosphate- and Mn⁺⁺ - dependent carboxylation of 664 moles of phosphoenolpyruvate per min per mole of enzyme at pH 7.0 and the ITP- and Mn⁺⁺ - dependent decarboxylation of 4650 moles of oxalacetate per min per mole of enzyme at pH 7.5. The enzyme exhibits a relatively high degree …
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Electrocatalytic Conversion of Carbon Dioxide to Value-Added Chemicals
… kinetic measurements. Electrocatalytic carboxylation of organic molecules with CO2 provides another pathway to generate high-value chemicals. We developed a methodology to perform electrocatalytic carboxylation without requiring sacrificial anodes. The key design principle involves …
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Investigation of the mechanism of action of pep carboxylase
… Since oxaloacetic acid, the phosphoenolpyruvate carboxylation product, is unstable under the reaction conditions, malate dehydrogenase and reduced nicotinamide-adenine dinucleotide were added in both assays to convert oxaloacetic acid to malic acid, which is stable. One assay method involves the …
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Isolation, characterization and expression ofcDNA and genomic sequences encoding ribulosebisphosphate carboxylase/oxygenase activase from barley
… (EC 4.1.1.39, rubisco) catalyzes either the carboxylation or oxygenation of ribulose-1,5-bisphosphate (RuBP) to initiate either the Calvin cycle or the photorespiratory pathway. Rubisco needs to be activated in order to catalyze these reactions. Rubisco activation involves the binding of an …
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Functionalised polymers
… of poly(vinyltoluene) by lithiation and carboxylation resulted in the expected carboxylic acid but reaction was complicated by the production of a mixture of products. Reaction occurred both at the polymer backbone and at the pendant methyl group. Reaction with ethyl formate was also …
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Effects of Activated Carbon on Reactions of Free and Combined Chlorine With Phenols (Chlorination, Gac)
… oxidation to quinones, chlorine substitution, carboxylation, and dimer formation.
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Light energy management in peach: utilization, photoprotection , photodamage and recovery. Maximizing light absorption in orchard is not always the best solution
… both because some photons are not used for carboxylation and an effective CO2 and reducing power loss occurs. Net photosynthesis increases with light until the saturation point, additional PPFD doesn’t improve carboxylation but it rises the efficiency of the alternative pathways in energy …
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Characterizing natural genetic variation in photosynthetic efficiency across 44 accessions and five subpopulations of oryza sativa
… were found at the biochemical level for carboxylation efficiency, maximum rate of carboxylation (Vcmax) maximum electron transport rate (Jmax), and triose-phosphate use (TPU) limitations – among 25 other traits. For example, subpopulation tropical japonica had the highest values for both …
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Photoredox activation of carbon dioxide and unactivated aliphatic carbonyl compounds
… catalyst effects the selective [alpha]-carboxylation of amines that bear various functional groups and heterocycles.
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The role of cysteine 230 and lysine 238 of biotin carboxylase in the deprotonation of biotin and synthesis of bisubstrate analogy inhibitor of carboxyltransferase
… biotin as a carboxyl carrier. In order for the carboxylation of biotin to occur, biotin must be deprotonated at its N-1 position. It has been proposed that the active site residues cysteine 230 and lysine 238 act as an acid-base pair to deprotonate biotin. To test this hypothesis, site-directed …
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Organic synthesis in suppercritical carbon dioxide
… both species on/in both phases. Three different carboxylation reactions were investigated in supercritical carbon dioxide. The Kolbe-Schmitt reaction (direct carboxylation of a phenolate salt) was found to proceed at high yields in supercritical carbon dioxide. Attempts at lowering the …
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(N-heterocyclic-carbene)Copper(I)-catalyzed carbon-carbon bond formation using carbon dioxide
… was developed. Alkynes undergo reductive carboxylation to give acrylic acids in moderate yields. Unexpected interactions between several components of the catalytic system led to a number of side reaction, most importantly between [(IPr)CuH]2 and the product silyl acrylate. The use of …
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Elucidating the Target and Selectivity of a Non-Small Cell Lung Cancer Toxin
… to mitochondrial inhibition use reductive carboxylation to meet aspartate demand, which suggests that targeting reductive aspartate synthesis would enhance clinical response to Complex I inhibitors.
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An EPR and DFT investigation of the products formed in the reaction of group 11 metal atoms with three-membered heterocyclic compounds
… have emerged as essential components in the carboxylation or metal-catalyzed ring expansion of three-membered heterocyclic compounds. Previous reports have speculated the presence of short-lived metal-substrate complexes and metallacyclic intermediates along the reaction path, yet to date …
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