Global ETD Search
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Showing 1 to 3 of 3 for “"carboxyalkanoates"”.
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Pullulan w-carboxyalkanoates for Drug Nanodispersions
… release. Successful synthesis of cellulose w-carboxyalkanoates have been reported and showed great promise as ASD polymers based on their ability to retard the recrystallization of the HIV drug ritonavir and antibacterial clarithromycin. However, these cellulose derivatives have limitations …
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Synthesis and Structure-property Evaluation of Novel Cellulosic Polymers as Amorphous Solid Dispersion Matrices for Enhanced Oral Drug Delivery
… a new series of organo-soluble cellulose omega-carboxyalkanoates for ASDs, by two different synthetic approaches. These carboxyl-containing cellulose mixed-esters possessed relatively high Tg values with sufficient differences versus ambient temperature, useful to prevent drug mobility and …
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Chemical Modification of Cellulose Esters for Oral Drug Delivery
… groups have revealed that some cellulose omega-carboxyalkanoates were highly effective as ASD polymers, with the pendant carboxylic acid groups providing both specific polymer-drug interactions and pH-triggered release through swelling of the ionized polymer matrix. While a variety of functional …