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Showing 1 to 20 of 22 for “"carbopol"”.
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Novel Carbopol-Wax Blends for Controlled Release Oral Dosage Forms
<p>Carbopol is crosslinked acrylic acid. Carbopol can be used in developing formulations for transdermal, oral, rectal use. It is forms strong gel in low concentration. Therefore, it can be used in low concentration in developing controlled release formulations. This increases the cost …
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The effect of Carbopol 934 rheological properties on the dissolution rate of sulphadamidine crystals.
… dissolution rate of a drug. For this the polymer Carbopol 934 (BF Goodrich) and a model drug, sulphadimidine, were chosen because their physicochemical properties could be changed by experimental variables, namely pH, temperature and salt concentration. Three forms of sulphadimidine were produced; …
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Desenvolvimento de hidrogéis à base de Carbopol 940® contendo sistemas de nanoprismas de prata/azul de metileno para inativação fotodinâmica de bactérias patogênicas
A Terapia Fotodinâmica (TFD) é uma abordagem promissora contra infecções bacterianas, baseada na interação entre um fotossensibilizador (FS), luz e oxigênio molecular. A inativação fotodinâmica (IFD) é uma estratégia eficaz contra microrganismos patogênicos, diferenciando-se da TFD pelo contexto de …
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Development of a platform for nasal delivery of peptides and vaccines using powder carriers based on starch/poly(acrylic) acid
… and a cross-linked acrylic acid-based polymer (Carbopol® 974P) was used as powder carrier to amplify the mucoadhesive capacity of the formulation. In a first part of the study, the Amioca®/Carbopol® powder formulation was subjected to a heat treatment procedure. After heat treatment the …
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Three Experiments on Complex Fluids
… and yielding of a simple yield-stress fluid (Carbopol 940) in a vertical pipe. The Carbopol was displaced from below by an immiscible Newtonian liquid (Fluorinert FC-40) injected at a constant, controlled rate. Rough and smooth-walled pipes were used to study the effects of wall boundary …
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Studies on the Formulation of Topical Corticosteroids
… gel with various polymers. Carbopol gel was the most cosmetically acceptable base. Stability studies of the corticosteroid in semi-aqueous Carbopol gels revealed that the decomposition pathway parallel those in aqueous propylene glycol. Steroid gels with a shelf-life of about …
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Nasal delivery of peptides using powder carriers based on starch/poly(acrylic acid)
… mixtures of Drum Dried Waxy Maize starch and Carbopol® 974P (ratio: 95/5, w/w) (DDWM/C 974P 95/5) and of spray-dried Amioca® starch and Carbopol® 974P (ratio: 25/75 and 85/15, w/w) (SD 25/75 and SD 85/15) were used. In Chapter 2 the characteristics of the components of the nasal powders were …
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YIELDING PHENOMENA IN MICROGEL SUSPENSIONS ACROSS LENGTH SCALES
… these questions, I primarily investigated Carbopol—a model microgel system—across different length scales, varying its swelling by adjusting pH or solvents. Microgel rheology in aqueous and non-aqueous solvents: By tuning pH, we investigated how microgel swelling affects their effective …
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Bio-inspired fluid locomotion
… foot on a mucus substitute such as Laponite or Carbopol. Robosnail 2 exploits the non-Newtonian qualities (yield-stress, shear thinning) of the fluid solution to locomote. The glue-like behavior of the unyielded fluid allows Robosnail 2 to climb up a 90 degree incline or inverted 180 degree …
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Development and formulation of wax-based transdermal drug delivery systems
… of additional excipients: Tween 20 (T), Carbopol®971 (C) and menthol (M) to the wax formulation. On in vitro permeation through porcine skin, the preferred formulations were: ibuprofen (5% w/w) within Witepsol®H15 + 1% w/w T; flurbiprofen (10% w/w) within Witepsol®H15 + 1% w/w T; naproxen …
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Development of a topical epigallocatechin gallate (EGCG) formulation
… EGCG's stability. Methacrylic acid derivatives (Carbopols RTM) were found to be the most efficacious gelling agents. Carbopol RTM 974, best known for its mucoadhesive properties, was found to produce the highest viscosity. In the last phase of the study EGCG was incorporated into the anhydrous …
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Development of semi-solid alkaline flow battery
… and designed suspending medium with jammed Carbopol© microgel structures to prevent sedimentation of the large particles. Secondly, we determined percolation threshold of conductive additive and investigated its effect on electrochemical performance of the semi-solid electrodes in a closed …
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Optimisation and validation of an alternative mucosal irritation test
… (die Amioca® zetmeel en lineair polyacrylzuur of Carbopol® 974P bevatten). Hiervoor werd de vijf dagen procedure van de mucosale irritatietest – die bij het begin van dit onderzoek aangewend werd voor de evaluatie van de lokale tolerantie van nasale bioadhesieve poeders – gebruikt. Er werd een …
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Grewia polysaccharide gum as a pharmaceutical excipient
… carboxymethylcellulose, guar and carbopol 971 P.
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Laminar heat transfer to Newtonian and Non-Newtonian fluids in tubes. Temperature and velocity profiles were determined experimentally for heating and cooling of Newtonian and non-Newtonian fluids in tubes and the results compared with theoretical predictions incorporating a temperature-dependent viscosity.
… be made. A Newtonian oil and two non-Newtonian Carbopol solutions were studied. This is the first time that velocity and temperature profiles have been measured for non-Newtonian fluids in this type of situation. The results of the work heve shown that (a) the velocity and temperature profiles …
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The influence of baseline hardness and chemical composition on enamel demineralization and subsequent remineralization
… were created in 94 bovine enamel specimens using Carbopol C907 using three demineralization times. The specimens were then pH-cycled and treated using either 367 ppm F sodium fluoride or a placebo. Knoop surface microhardness (SMH), Energy dispersive X-ray spectroscopy (EDS) and Transverse …
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Taking Magnetic Resonance into Industrial Applications
… of model Herschel--Bulkley fluids, namely Carbopol 940-in-water solutions; data are acquired in only 12% of the time required for analysis using MR flow imaging. The suitability of the Bayesian MR approach to study process fluids is demonstrated through experimental study on an …
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Desenvolvimento e avaliação biofarmacotécnica/farmacodinâmica de formulações tópicas contendo betametasona
… do tipo O/A, que foram veiculadas em gel de Carbopol® para incremento de viscosidade. Todas as formulações apresentaram pH na faixa de tolerância da pele; tamanho de gotícula de 14,67±0,2 a 37,56±0,8; potencial zeta negativo, entre -3,596 e -1,407 mV e mostraram-se isotrópicas através da MLP. …
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Desenvolvimento de hidrogel semissólido contendo óleo essencial de Cymbopogon citratus (DC.) Stapf carreado em nanopartículas poliméricas para o tratamento tópico da herpes
… NPOE foram incorporadas a gel hidrofílico de Carbopol® Ultrez 10 NF (HNPOE), a fim de investigar a estabilidade da formulação nanoestruturada frente ao armazenamento e o perfil de liberação in vitro do óleo a partir da nanopartícula. Adicionalmente, hidrogel base (HB), hidrogel contendo o óleo …
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The Effect of Silver Diamine Fluoride on Caries Lesion Remineralization as a Function of Lesion Baseline Mineral Distribution
… [MeC], hydroxyethylcellulose [HEC], Carbopol [C907]), artificial caries lesions with different mineral distributions (n=20 per subgroup) were created in the enamel specimens Interventions were applied and the lesions remineralized using artificial saliva. Changes in mineral loss, …
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