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Showing 1 to 20 of 69 for “"carbonic anhydrase"”.
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Carbonic anhydrase in the marine diatom Thalassiosira weissflogii
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 1995.
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Enantioselective epoxidation catalyzed by manganese-substituted human carbonic anhydrase
… The generation of a thermostable human carbonic anhydrase mutant, activity determination, generation of an artificial metalloenzyme (manganese-substituted human carbonic anhydrase) and its use as a catalyst for enantioselective epoxidation of olefins is also described.</p>
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Crystallographic studies of carbonic anhydrase isoforms and their complexes with inhibitors /
Crystallographic studies of carbonic anhydrase isoforms and their complexes with inhibitors The goal of this study was 1) to solve the crystal structures of the complexes of several CA isoforms with a series of sulfonamide inhibitors using X-ray crystallography technique, 2) to analyze the …
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Zero length crosslinking of bovine carbonic anhydrase II and chondroitin-4-sulfate
Bovine carbonic anhydrase II (EC 4.2.1.1) was covalently linked to chondroitin-4-sulfate (β-glucoronic acid-[1-3]-N-acetyl-β-galactosamine-4-sulfate-[1-4]) from bovine trachea. A zero length crosslinking procedure which reacts the protein amino groups with preactivated carboxyl groups of …
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The Relationship of Carbonic Anhydrase to Mineralization in The Epiphyseal Cartilage of Rats
Made available in DSpace on 2014-12-09T23:33:46Z (GMT). No. of bitstreams: 1 6402967.pdf: 3677204 bytes, checksum: 215c1c82f3a66f1a903c90097da2ea72 (MD5) Previous issue date: 1963
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Structure, Function and Applications of Metal-Requiring Enzymes: Carbonic Anhydrase and Epi-Isozizaene Synthase
Cryptophane Biosensors for Targeting Human Carbonic Anhydrase Cryptophanes represent an exciting class of xenon-encapsulating molecules that can be exploited as probes for nuclear magnetic resonance imaging. A series of carbonic anhydrase-targeting, xenon-binding cryptophane biosensors were …
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Plastidial carbonic anhydrase in cotton (Gossypium hirsutum L.): characterization, expression, and role in lipid biosynthesis
Recently, plastidial carbonic anhydrase (CA, EC 4.2.1.1) cDNA clones encoding functional CA enzymes were isolated from a nonphotosynthetic cotton tissue. The role of CA in photosynthetic tissues have been well characterized, however there is almost no information for the role of CA in …
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The Transport of Carbon Dioxide in Bicarbonate Solutions: Studies of Fluxaugmentation and the Properties of Carbonic Anhydrase
Made available in DSpace on 2014-12-10T21:24:46Z (GMT). No. of bitstreams: 1 7121198.pdf: 6000580 bytes, checksum: e2bfc19773ecbf7309aae90b394ee02d (MD5) Previous issue date: 1971
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Quantitative cytochemical studies of acid secretagogue effects on the carbonic anhydrase activity of gastric parietal cell sections
This thesis presents work designed to study the effects of acid secretagogues upon the parietal cell, in order to gain a greater understanding of their modes of action, and interaction and the role of circulating secretagogues in the mediation of parietal cell function, with the aim of increasing …
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(I) Zinc complexes as synthetic analogues for carbonic anhydrase and as catalysts for H₂ production and CO₂ functionalization . . .
… are of relevance to the mechanism of action of carbonic anhydrase. Low temperature ¹H and ¹³C NMR spectroscopic studies on solutions of the hydroxide complex, [Tpᴮᵘᵗ𝄒ᴹᵉ]ZnOH, in the presence of 1 atmosphere of CO₂ have allowed for the identification of the bicarbonate complex, [Tpᴮᵘᵗ𝄒ᴹᵉ]ZnOCO₂H. …
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Population Frequencies of Carbonic Anhydrase (CA II), Esterase D (EsD), and Glyoxalase I (GLO) in the Metropolitan Birmingham Area.
The identification of individual source is one of the main objectives of the forensic serologist when analyzing blood, bloodstains, or other body fluids. Certainly, the more we know about a specific blood sample, the more we can learn about an alleged criminal act. All individuality is due to …
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DEVELOPMENT OF BISPECIFIC T CELL ENGAGERS TARGETING CARBONIC ANHYDRASE 9 FOR THE IMMUNE THERAPY OF CLEAR CELL RENAL CELL CARCINOMA
… treat advanced ccRCC by targeting the antigen, carbonic anhydrase 9 (CA9), while characterizing the clinically relevant Persistent BTE (PBTE) format, advancing its design concept, and testing in vivo delivery through synthetic DNA (dBTEs). We show that, compared to a prototypical BTE, PBTE …
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Design of Nanostructured Peptoid Assemblies as Synthetic Analogues of Natural Carbonic Anhydrases
… solution to the reduction of atmospheric CO2 and carbonic anhydrase functions as a natural carbon dioxide hydrase to hydrate carbon dioxide efficiently. However, carbonic anhydrase (CA) encounters multiple extraction and preservation difficulties and can easily become inactivated. Thus, …
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An atlas of the choroidal ultrastructure with the histochemical localization of choroidal and pseudobranchial carbonic anhydrase activity in the rainbow trout (Salmo gairdneri)
Thesis (M.S.)--Michigan State University. Dept. of Physiology, 1975
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Carbonic anhydrase from Methanosarcina thermophila: proposal of a new class of carbonic anhydrases and putative roles for the enzyme in anaerobic acetate catabolism
Carbonic anhydrase (CA) from acetate-grown Methanosarcina thermophila strain TM-1 was purified> 10,OOO-fold (22% recovery) to apparent homogeneity and a specific activity of 4,900 units mg⁻¹.The gene encoding this CA was isolated fronl a partial genomic library on a 12-kb fragment and sequenced. …
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Development of novel reactive oxygen species (ROS)-modulating agents and carbonic anhydrase inhibitors for the treatment of Pancreatic Ductal Adenocarcinoma and other resistant cancers
… propose the study of a novel class of selective carbonic anhydrase inhibitors (CAI) targeting the human isoforms IX and XII (hCA IX and XII) overexpressed in several cancer types. Additionally, I propose the development of a serie of multivalent inhibitors designed to optimize both selectivity …
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Effects of Cadmium on Calcium homeostasis and physiological conditions of the freshwater Mussel Anodonta anatina
… homeostasis, condition index, energy reserves, carbonic anhydrase activity and their correlations were examined and evaluated. Before mussels were exposed to Cd, a Cd-exposure experiment with the green algae Parachlorella kessleri was carried out for producing 111Cd-loaded algae suitable for …
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The use of purified enzymes for the early assessment of toxicity
… enzymes: α-chymotrypsin, acid phosphatase, and carbonic anhydrase for use in the early assessment of toxicants at environmentally significant levels. Activities of α-chymotrypsin and acid phosphatase were measured spectrophotometrically, while carbonic anhydrase activities were determined …
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