Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 105 for “"carbon metabolism"”.
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Regulation of Alternative Carbon Metabolism In Candida Albicans
… activating genes involved in alternative carbon metabolism, including the glyoxylate cycle, β-oxidation and gluconeogenesis. Mutations in key enzymes such as ICL1 (glyoxylate cycle) and FOX2 (fatty acid β-oxidation) revealed that alternative carbon metabolic pathways are required for full …
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Characterization of The Ato Gene Family In Alternative Carbon Metabolism
… release (Ammonia Transport Outward) and acetate metabolism. I hypothesized that the Ato proteins are important effectors of the pH change <em>in vitro</em> and in macrophages. Deletion of one of the 10 homologs, <em>ATO5, </em>or the over-expression of a dominant negative <em>ATO1<sup>G53D</sup> …
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Subcellular compartmentation of primary carbon metabolism in mesophyll cells of Arabidopsis thaliana
Metabolismus in Pflanzenzellen ist stark kompartimentiert. Viele Stoffwechselwege haben Reaktionen in mehr als einem Kompartiment. Zum Beispiel wird während der Photosynthese in pflanzlichen Mesophyllzellen Kohlenstoff in Form von Stärke in den Chloroplasten synthetisiert, während es im Zytosol in …
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Identification and characterization of novel Rhizobium meliloti genes involved in carbon metabolism
Thesis (Ph. D.)-Massachusetts Institute of Technology, Dept. of Biology, 1998.
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A study of the phylogenetics, nutrition and one-carbon metabolism of Syntrophococcus sucromutans
Syntrophococcus sucromutans is phylogenetically included in the Gram-positive phylum of the Eubacteria, by virtues of 16S ribosomal RNA sequence similarity analysis. It is part of a well defined genealogic entity described as the Butyrivibrio subdivision which, like the Sporomusa subdivision …
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The relationship of folic acid compounds to one-carbon metabolism in the tabacco plant
Thesis (M.S.)--Michigan State University of Agriculture and Applied Science. Dept. of Chemistry, 1958
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Regulation of Photosynthetic Carbon Metabolism in Isolated Spinach Chloroplasts Under Photorespiratory and Non-Photorespiratory Conditions
… of several added metabolites on photosynthetic carbon metabolism in isolated spinach chloroplasts were examined. Under conditions of ambient O(,2), saturating HCO(,3)('-) and a range of phosphate concentrations (0.1-10 mM), PGA and DHAP (1-6 mM each) reduced ('14)CO(,2) fixation by 60% of the …
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Carbon-13 metabolic flux analysis of soybean central carbon metabolism: response to temperature and genotype effects
… unknown;Metabolic flux analysis (MFA) quantifies carbon flow in a biological system, which is an important characteristic reflective of the system physiology. The application of MFA to study complex plant metabolic networks has however been recent. Towards this goal, MFA using carbon labeling …
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Interactive effects of elevated carbon dioxide concentration with nutrient availability and leaf development on plant carbon metabolism
The balance between photosynthetic carbon dioxide (CO2) assimilation and respiratory CO2 release influence plant growth, crop yields, and the ability of terrestrial ecosystems to offset ~2-3 Gt CO2 yr -1 of anthropogenic emissions. Rising atmospheric CO2 concentration ([CO2]) this century will …
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We are what we eat : identifying a regulatory crosstalk between central carbon metabolism and cell division in bacteria
… events with the nutrient availability. Central Carbon Metabolism (CCM), being the entry point for almost all the raw materials required for cellular growth and proliferation, forms the hub for coordinating nutrient availability to cell growth, size and the division process. Our lab recently …
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Characterizing the role of central carbon metabolism and cell wall stress responses in Bacillus subtilis cell wall synthesis
… GlmR functions at the interface of the central carbon metabolism and the peptidoglycan biosynthesis pathway. I have discovered that under gluconeogenic growth condition, GlmR plays an essential role in diverting carbon from the central carbon metabolism to the peptidoglycan biosynthesis, …
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An investigation of the role of CreB deubiquitinating enzyme in the regulation of carbon metabolism in Aspergillus nidulans
In A. nidulans, carbon catabolite repression is regulated by the global repressor protein CreA which, in the presence of repressing carbon sources, represses those genes that are required to utilize less preferable carbon sources. Mutational analyses suggested that ubiquitination, mediated by CreD …
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Maternal rumen-protected methionine supplementation alters dairy calf development, postnatal growth, plasma biomarkers, and liver one-carbon metabolism
… metabolomics via GS-MS and activity of hepatic 1-carbon metabolism enzymes. Liver samples at day 4 were used for RNA sequencing, protein expression, and global DNA methylation. Blood for biomarker analyses and innate immune function assays was harvested at birth (before colostrum feeding), 7, 21, …
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Carbon metabolism and dissolved organic carbon (DOC) fluxes on seagrass communities: insights from plant colonization states, eutrophication and global change related factors
… ecosystems on Earth. Their role in the global carbon cycle and how they cope with global change may be more relevant than previously believed. They export large quantities of matter, both in particulate and dissolved forms to adjacent communities. Dissolved organic carbon (DOC) flux play a …
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Design and Synthesis of Pyrimidine Based Heterocycles as Potential Anti-cancer Agents with Combination Chemotherapeutic Potential or Targeted One Carbon Metabolism Inhibition and Anti-opportunistic Agents
… effects and cytotoxic effects or b) one-carbon metabolism inhibitors for targeted tumor therapy; or c) selective <em>Pneumocystis jirovecii </em>(pj)<em> </em>dihydrofolate reductase (pjDHFR) inhibitors for pneumocystis pneumonia (PCP) infection.</p> <p>The work in this dissertation is …
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Development of 13C Fingerprint Tool and Its Application for Exploring Carbon and Energy Metabolism in Cyanobacterium Synechocystis sp. PCC 6803
… that cyanobacteria will provide much higher carbon yield than heterotrophs by co-utilizing organic carbons and CO2. However, the quantitative information of such `photo-fermentation' process is still limited. Decoding the carbon metabolism of cyanobacteria during the photo-fermentation …
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MOLECULAR DRIVERS OF DISEASE PATHOGENESIS IN NONALCOHOLIC STEATOHEPATITIS
… proteomics identified dysregulation of one-carbon metabolism in NASH. This dissertation details the molecular mechanisms for how these proteomic changes can drive NASH pathogenesis and be targeted for therapeutic purposes. Chapter 1 provides an extensive background on NASH prevalence and …
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