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Showing 1 to 9 of 9 for “"carbohydrate antigen"”.
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CA 125 como marcador de mortalidad en pacientes con falla cardiaca descompensada: Revisión sistemática de la literatura y metaanálisis
… MESH heart failure, heart disease, CA-125 antigen, carbohydrate antigen-125 y MUC16, seleccionando estudios en inglés y español entre el 1 de enero de 2000 y el 31 de julio de 2024. Se incluyeron ensayos clínicos, estudios de cohortes prospectivas o retrospectivas, y casos y controles. El …
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Kasos adenokarcinomos diagnostinių ir prognostinių biožymenų paieška /
… mass spectrometry. Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) was discovered as a possible promising pancreatic cancer biomarker. The predominance of CEACAM6 to pancreatic cancer was validated using antibodies in tissue samples. CEACAM6, carbohydrate antigen …
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MicroRNAs in Pancreatic Ductal Adenocarcinoma: New Approaches For Better Diagnosis And Therapy
… the standard of care for patients with PDAC. Carbohydrate antigen 19-9 (CA 19-9) is the most common diagnostic biomarker; however, it is not specific enough for asymptomatic patients. MicroRNAs (miRs/miRNAs) are small non-encoding RNA molecules, which have been related with PDAC progression …
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PERSPECTIVES ON THE CLINICAL APPLICATION OF LEWIS ANTIGENS IN PANCREATIC CANCER: TOWARDS A PERSONALIZED TUMOR MARKER STRATEGY
Background. Carbohydrate antigen 19.9 (CA19.9) is used as a tumor marker in gastrointestinal cancers, assuming that it is produced by cancer cells. Recent data has suggested that, in pancreatic ductal adenocarcinoma (PDAC), elevation of CA19.9 could depend on its reabsorption in the bloodstream. No …
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Biological Evaluation Of The Vaccine Candidate Tf-Ps A1 And A One-Pot Multicomponent Coupling/cyclization For Natural Product Herbicide (±)-Thaxtomin A
… of the Thomsen–Friedenreich tumor associated carbohydrate antigen has been synthesized in 11 steps utilizing a D-GalN3 acceptor carrying a pre-installed -N-hydroxysuccinimidyl moiety. The natural linkage was prepared in high selectivity employing a suitably protected D-GalN3-thioglycoside …
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Advancing Technologies for Precision Medicine: From Liquid Biopsy to Single-Molecule DNA Sequencing
… compared to the commonly used serum biomarker carbohydrate antigen 19-9 (CA19-9). Genomic DNA extracted from the isolated CTCs was subjected to whole-genome amplification followed by next-generation sequencing to identify mutations in DNA damage repair genes, while KRAS (Kristen rat sarcoma) …
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Synthesis and Characterization of Multi-Functional Nanoparticles for Therapeutic and Biosensing Applications
… two different cancer markers — carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9) from diluted whole blood or undiluted serum, on a paper-based microfluidic platform. These particles were covalently conjugated with anti-CEA and anti-CA 19-9 antibodies and stabilized with BSA. …
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SYNTHESIS AND STUDY OF ANTI-TUMOR VACCINES
<p>The inherent weak immune response against carbohydrate antigens has directed several novel approaches towards increasing their immunogenicity for their use as vaccine components. We hypothesized that conjugation of an L-rhamnose (Rha) moiety to a carbohydrate antigen would increase the immune …
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New Carbohydrate-Based Anti-Cancer And Anti-Bacterial Vaccines
<p>The unique carbohydrates expressed on the surface of cancer, bacterial, viral and fungal cells are excellent target antigens for the design of therapeutic or preventive vaccines. However, as antigens carbohydrates have problems. First, carbohydrates usually have low immunogenicity. Second, even …