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Showing 1 to 20 of 51 for “"carbachol"”.
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Carbachol-Induced Pigment Granule Dispersion
… macrochirus) RPE, I examined the effects that carbachol and acetylcholine analog, has on pigment granule dispersion in a dose-dependent manner, and the maximum effects of carbachol were observed at concentrations as low as 10 nM. Atropine was highly effective in blocking carbachol-induced …
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Carbachol- and ACPD-Induced Phosphoinositide Responses in the Developing Rat Neocortex
… somatosensory cortex. The acetylcholine agonist carbachol and the glutamate agonist trans-1-amino-1,3-cyclopentanedicarboxylic acid (ACPD) were used to stimulate PI turnover. The PI responses were compared to the distribution of the corresponding PI-linked receptors in order to investigate the …
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Affective Reactions of Rats to Norepinephrine and Carbachol in the Hypothalamus
Made available in DSpace on 2014-12-10T21:07:19Z (GMT). No. of bitstreams: 1 7212193.pdf: 2800140 bytes, checksum: 365ee68f96a55cc9c39f61de49370b13 (MD5) Previous issue date: 1971
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Autoradiographic Localization of Carbachol-Induced Second Messenger Response in the Rat Spinal Cord Following Inflammation.
… the highest levels of baseline PI turnover and carbachol-stimulated PI turnover in normal animals as well as after inflammation. Inflammation resulted in increased baseline PI turnover in this region of the ipsilateral (76%) and contralateral (65%) dorsal horns. Carbachol increased PI turnover …
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Adrenergic-cholinergic interactions in the heart
… myocardium the muscarinic receptor agonist carbacholcan inhibit the positive inotropic responses to isoproterenol, a f3-adrenoceptor agonist, forskolin, a direct activator of adenylate cyclase, IBMX, a phosphodiesterase inhibitor, and phenylephrine, an a-adrenoceptor agonist. While the …
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Comparison Of Affective Analgesia And Conditioned Place Preference Following Cholinergic Activation Of
… microinjections of the acetylcholine agonist carbachol suppressed vocalizations of rats that occur following administration of brief (1 sec) tail-shocks (vocalization afterdischarges = VAD). VADs are a validated rodent model of pain affect. In addition, the capacity of carbachol to support …
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The role of the GABAergic system in the production of ultrasonic vocalization in rats /
… have found that intracerebral injection of carbachol, a predominantly muscarinic agonist, into die anterior hypothalamic/preoptic area (AH/POA) rehably induces vocalization similar to naturally emitted ultrasonic calls. It has also been shown that carbachol has extensive inhibitory effects …
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Signalling to intracellular Ca2+ channels
… by L-type Ca$^{2+}$ channels. Both caffeine and carbachol evoked Ca$^{2+}$ entry and release. Caffeine-evoked Ca$^{2+}$ entry was inhibited by ryanodine and nimodipine. This might be due to direct activation of RyR in the PM, or activation of other Ca$^{2+}$-permeable channels in the PM secondary …
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Regulation of duodenal mucosal bicarbonate secretion
… intestinal polypeptide, prostaglandin E2, carbachol and theophylline are the chief agonists of duodenal bicarbonate secretion. Vasoactive intestinal polypeptide and prostaglandin E2 act directly via distinct receptors on the duodenal enterocytes, activating adenylate cyclase and protein …
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Postsynaptic Cholinergic Control Of Cardiac Function In Aging
… but the muscarinic receptor binding affinity for carbachol, a cholinergic agonist, was increased in the atria but not ventricles of aged compared to adult rats. (iii) The relative amount of {dollar}rm Gialpha{dollar} protein measured by Western immunoblotting and ADP-ribosylation techniques was …
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Immunohistochemical study of laterodorsal tegmental neurons active during 22kHz vocalization /
… active during air puffinduced vocalization than carbachol-induced one. Choline acetyltransferase (ChAT), and cFos protein were visualized histochemically as markers of cholinergic calls and cellular activity, respectively. Results indicated that animals vocalizing after carbachol, but not after …
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The role of reactive oxygen species in the endothelium derived hyperpolarising factor response
… while preventing the synthesis of NO and PGI2. Carbachol (10 μM) caused a 74.5 ± 2.3% (n = 65) relaxation and the 360/380 nm ratio increased by 25.6 ± 1.6% (n = 69). Both responses were substantially reduced by a ROS scavenging combination of superoxide dismutase and catalase (100 U.ml-1 each). …
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Nitric oxide in the rat gastrointestinal tract
… mucosa, (iii) to investigate the role of NO in carbachol-stimulated gastric mucus secretion, (iv) to investigate the nature of NOS and small intestine. Immunoblotting was performed using polyclonal antisera raised against two peptides found in the rat brain NOS sequence and commercial monoclonal …
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The role of a monomer/dimer equilibrium and the C-terminal tail in regulating translocation of sphingosine kinase 1 to the plasma membrane of breast cancer cells
… PM of MCF-7L breast cancer cells. In addition, carbachol also induced translocation of WTmGFP-SK1 to lamellipodia, albeit in an ERK-independent manner.;In contrast, S1P induced the ERK-independent translocation of WTmGFP-SK1 to filopodia. Treatment of cells with either the phospholipase D (PLD) …
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Defining Ankyrin-b Syndrome: Characterization of Ankyrin-b Variants in Mice and Men and the Discovery of a Role for Ankyrin-b in Parasympathetic Control of Insulin Release
… of insulin secretion by the muscarinic agonist carbachol, blunted carbachol-mediated intracellular Ca2+- release, and reduced InsP3R stability. Ankyrin-B(+/-) mice also display postprandial hyperglycemia, consistent with impaired parasympathetic potentiation of glucose-stimulated insulin …
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Cholinergic regulation of a mammalian circadian clock
A cholinergic agonist, carbachol, has been shown to shift the phase of circadian rhythms in rodents when injected intracerebroventricularly. However, the site and receptor type mediating this action have been unknown. The suprachiasmatic nuclei (SCN), the primary circadian pacemaker in mammals, …
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Using Conditioned Food Aversion (CFA) to reduce Pied Crow (Corbus albus) predation of plover nests
… whether provisioning quail eggs treated with carbachol, an illness-inducing chemical, resulted in reduced nest predation. To assess the effects of treatment, nest survival data for both artificial plover nests containing quail eggs and natural Kittlitz's plover nests, as well as predator …
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AN INVESTIGATION OF THE MECHANISM BY WHICH ALUMINIUM AND OTHER POLYVALENT CATIONS INHIBIT ECCRINE SWEATING
… animal by systemic administration of carbachol (0,0025-2500 ug/kg) or by local intradermal administration (0.75 µg in 0,01 ml of isotonic saline) of carbachol and methacholine and also by localised heat stress, These effects could all be reduced or abolished by prior administration of …
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Interactions between the cholinergic and dopaminergic system during the production of ultrasonic vocalizations in rats
… accumbens significantly decreased the number of carbachol-induced 22 kHz USVs from both AH-MPO and LS. Injection of carbachol into the LS significantly decreased the number of apomorphine-induced 50 kHz USVs from the shell of the nucleus accumbens. The results of the study supported the main …
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Nongenomic Effects of Estrogens on Epithelial Chloride Secretion.
… rapidly (within seconds to minutes) potentiates carbachol- and thapsigargin-stimulated chloride secretion measured as short circuit current in voltage-clamped T84 monolayer cultures. The cholinergic agonist carbachol and the SR Ca<sup>2+</sup> ATPase inhibitor thapsigargin stimulate chloride …
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