Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"capecitabine"”.
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Capecitabine Induced Hand and Foot Syndrome and the Reproducibility of Friction Skin
… as a result of his cancer treatment of capecitabine (N4-pentyloxycarbonyl-5-deoxy-5- fluorocytidine) which causes interruptions to the normal growth of keratinocytes in the friction skin. Capecitabine is a recently developed, orally administered fluoropyrimidine prodrug designed to …
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An exploratory study to identify risk factors for the development of capecitabine-induced Palmar Plantar Erythrodysesthesia (PPE)
… of patients who had received Infusional 5FU or capecitabine containing regimes over a 1 year period (n=392). Phase II Prospective data collection from participants receiving capecitabine monotherapy (n = 125). Data was collected during semi-structured interviews, from participant’s diaries, …
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How do New Zealand nurses who work in the area of oncology educate and provide follow-up support to patients who are prescribed oral capecitabine and what are nurses’ perceptions of this process?
… about this prior to commencing therapy. Capecitabine is an oral chemotherapy prescribed to treat gastro-intestinal and bowel cancers. This therapy has been in New Zealand for approximately fifteen years. As New Zealand has one of the highest rates of bowel cancer worldwide, capecitabine …
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현미부수체 상태에 따른 결장암의 예후와 보조항암요법과의 상관관계
… 결장암의 특성을 분석하였으며, 75명의 3기 결장암 환자를 대상으로 FOLFOX 또는 capecitabine을 투여한 결과를 후향적으로 분석하였다. MSI 결장암의 경우 5년 생존율은 비슷하였으나 (92.3% vs 85.5% p=0.608) 원발종양이 근위부에 위치하고 (86.7% vs 42.3% p<0.001) 병리학적으로 점액성암의 빈도가 높고 암세포의 분화도가 좋게 나왔다. (p<0.001) 3기 결장암에서 FOLFOX치료를 받은 환자군은 capecitabine 투여를 받은 환자군보다 유의한 생존율 향상을 보이지 않았으며 …
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Metabolomics and chemical library screening for antibacterial drug discovery
… against MRSA after microsomal metabolism e.g. capecitabine, balofloxacin, gatifloxacin. A second dimension involved screening in the presence and absence of cefoxitin to identify synergistic agents. Several drugs exhibited synergy with cefoxitin against MRSA that includes floxuridine, …
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The impact of cytotoxic chemotherapy on somatic mutation in normal human cells
… be mutagenic *in vivo*, including 5-fluorouracil/capecitabine and topoisomerase II inhibitors. Alongside the requirement for repeated treatment *in vitro*, this suggests that antimetabolite- associated mutagenesis may be restricted to dividing cells, suggesting that mechanism of action influences …