Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 26 for “"cancer stage"”.
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Examination of Racial/Ethnic Disparities in Ovarian Cancer Stage of Diagnosis, Surgery Treatment and Survival: Multilevel Analysis of 2001-2012 SEER Data
<p><em>Context.</em> Racial/ethnic disparities in cancer outcomes are major public health concerns. Ovarian cancer is the tenth most common cancer and the fifth leading cause of cancer-related deaths among women. Identifying individual- and contextual-level factors contributing to racial/ethnic …
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Optimism, Health Locus of Control, and Quality of Life of Women with Initial versus Recurrent Breast Cancer
… women with an initial versus recurrent breast cancer diagnosis. Twenty-eight women with an initial breast cancer (IBC) diagnoses and twenty-eight women with recurrent breast cancer (RBC) diagnoses were recruited from doctors' offices and cancer support groups. Correlational analyses were used …
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Estimating the treatment cost of colon cancer at Groote Schuur Hospital
… the high mortality-to-incidence ratio of colon cancer in South Africa, urgent public health measures are needed to improve treatment outcomes. Costing studies can be leveraged to understand the treatment cost burden for colon cancer, providing crucial insights for allocating resources to finance …
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Breast cancer incidence and stage at diagnosis in Ontarians with and without intellectual disabilities
This thesis examines breast cancer incidence and stage at diagnosis in Ontarians with and without intellectual disabilities. The objectives were 1) To describe and compare the incidence of breast cancer in women with and without intellectual disabilities from 2000 to 2014; 2) To describe and …
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Effects of Diabetes on Ovarian Cancer: Data Analysis and Modeling Study
<p>Ovarian cancer has one of the highest mortality rates of all gynecological cancers [13]. Further knowledge of risk factors for the growth of ovarian tumors would be beneficial in both the treatment and prevention of this type of cancer. Previous research has shown a positive correlation between …
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An Analysis of the Efficacy of Cervical Cancer Screening in Elderly Women
… study utilized 2,778 incident cervical cancer cases from the Surveillance, Epidemiology and End Results (SEER) program registries that were diagnosed between 1991 and 1999. Population controls (N=10,137) were matched on age and geographical location to cases and were identified through a …
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The Association between Serum Cancer Antigen 125 (CA 125) and Risk of Lung Cancer in Females: Assessing the Possibilities for Early Detection
… the relationship between CA 125 and lung cancer. This study is expected to provide more understanding about CA 125 and its role as a potential predictor for lung cancer risk. Objectives: To evaluate: i) the association between CA 125 and lung cancer; ii) if the associations differ by …
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Self-care activities and quality of life in ovarian cancer survivors
… factors affect quality of life in ovarian cancer survivors. Three hypotheses were derived from the research question: (a) self-care activities are predictors of quality of life, (b) period of cancer survivorship is a predictor of quality of life, (c) selected basic conditioning factors are …
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Fruit and vegetable intake and quality of life among breast cancer survivors
Background: With advances in breast cancer detection and treatment, survivors now have a 5-year survival rate > 90%. This has led to a shift in focus to improving not only survival, but also health-related quality of life (HR-QoL) after diagnosis, including physical, social, emotional, functional, …
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Estimating telomere length from whole genome sequencing data
… that Telomerecat lends itself well to analysing cancer samples where such assumptions are unfounded. This also means it is applicable to non-human samples, a first for tools of its kind. Furthermore, a novel method for filtering reads derived from interstitial telomere sequences means that it …
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Posttraumatic Growth in Survivors of Breast Cancer: The Role of Dispositional Optimism, Coping Strategies, and Psychosocial Interventions
… experience of posttraumatic growth for breast cancer survivors who volunteered to complete a survey (N = 277). A number of participants also provided narrative responses containing their personal experiences of breast cancer (N = 100). Demographic characteristics, breast cancer variables, …
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Triage-driven diagnosis for early detection of oesophageal cancer
… survival is less than 20%. However, if the cancer can be diagnosed at an early, superficial stage then treatment can be performed endoscopically and over 80% of patients survive beyond 5 years. The disease has a clear pre-cancer stage called Barrett oesophagus, making early detection …
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The Role of Three-dimensional Ultrasound in the Diagnosis and Treatment of Uterine Pathology
… in the diagnosis and treatment of endometrial cancer. Currently women with postmenopausal bleeding are investigated by transvaginal ultrasound to measure endometrial thickness. This results in a substantial 22 number of women needing endometrial biopsy to confirm benignity. We evaluated the …
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A prospective examination of change in executive function and physical activity in older breast cancer survivors
Only one third of older breast cancer survivors (BCS) meet national physical activity (PA) guidelines. Theories of self-regulation and research with older adults suggest that executive function (EF) plays an important role in PA, yet the impact of lower EF on older survivors’ PA is unknown. My …
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Cognitive Dysfunction in Older Breast Cancer Survivors
Up to 75% of the more than 3.5 million breast cancer survivors (BCS) living in the United States report cognitive dysfunction. However, little is known about cognitive dysfunction among older BCS, who may be at greater risk. Therefore, the purpose of this dissertation was to characterize cognitive …
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Obesogenic Environment and Prostate Cancer Prognosis in Chicago, IL
Obesity has been linked to aggressive prostate cancer, suggesting that environments promoting obesity—referred to as obesogenic environments—may influence prostate cancer progression and mortality at the population level. While prior population-based studies have primarily examined the role of …
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The RESILIENT Study: A Retrospective, Descriptive, Correlational Investigation of Rate and Correlates of Oral Endocrine Therapy Adherence in Older Women with Breast Cancer
Breast cancer is the most prevalent and costly cancer among females. About 80% of breast cancer patients take oral endocrine therapy (OET), such as anastrozole, letrozole, tamoxifen, and exmestane. These medications increase survival, improve quality-of-life and decrease healthcare costs, yet many …
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Sleep/wake patterns and key predictors for sleep impairment in patient-caregiver dyads:: a longitudinal observational study among women with early stage breast cancer and their informal caregivers during chemotherapy treatment
… sleep/wake patterns of women with breast cancer and their informal caregivers may be concurrently exacerbated and co-vary during the patient’s treatment. The current study set out to longitudinally ex-plore sleep-wake patterns of patient-caregiver dyads in the context of adjuvant …
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Treatment outcomes of Her-2 positive Breast Cancer in the absence of Her-2 targeting agents at Groote Schuur Hospital, Cape Town, South Africa. Are we doing enough?
Purpose: Breast Cancer has an estimated 2.3 billion cases globally. It is the second most common cause of cancer-related mortality in Sub-Saharan Africa. The addition of anti- Her-2 targeted therapy (Trastuzumab) to either adjuvant or neo-adjuvant treatment significantly improves disease-free …
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Novel therapies for cancer treatment : designing high affinity selective ligands against SIRT1 enzyme
… cytoplasm. Many Sirtuins targets are involved in cancer and in many types of cancers, SIRT1 is found to be overexpressed. Recent observations support SIRT1 being both an oncogene and a tumour suppressor, depending on the cancer etiology and type of tissue. To answer the question “How can SIRT1 …
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