Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 45 for “"cancer recurrence"”.
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Psychological Adjustment to Uncertain Outcomes: The Threat of Cancer Recurrence
… reports suggest that follow-up exams to detect cancer recurrence can be very stressful, yet recent research posits that most cancer patients recover emotionally from their diagnosis over the one to two years after diagnosis and treatment. The present study employed a limited, longitudinal design …
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Understanding Women's Concerns and Coping with Worry of Breast Cancer Recurrence
Worry of cancer recurrence is prevalent among survivors of breast cancer. It can persist for years and undermine women's psychological wellbeing and overall adjustment. Thus far, we have limited knowledge about the individual, treatment and psychosocial characteristics that account for variations …
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Relationship of Illness Perception and Fear of Cancer Recurrence to Psychological Distress among Gynecologic Cancer Survivors
Gynecologic cancer survivors account for approximately 9% of all cancer survivors, and about 40% of the gynecologic cancer survivors have been reported to experience some form of psychological distress. Further, fear of cancer recurrence is prevalent among gynecologic cancer survivors, and illness …
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Do Finances Determine Our Fate?: Understanding the Relationships Between Socioeconomic Status, Inflammation, and Cancer Recurrence Risk
… status (SES) are more likely to experience a cancer recurrence relative to individuals with a higher SES. This may be partially explained by the stressors of living with a low SES. These stressors can increase inflammatory markers known to elevate the risk of cancer development. …
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Off the shelf: Toward implementation of an evidence-based psychological intervention for fear of cancer recurrence
Contains fulltext : 317679.pdf (Publisher’s version ) (Open Access)
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The relationship between body mass index and breast cancer recurrence/progression and breast cancer-specific death
… between body mass index (BMI) and breast cancer outcomes and to determine whether BMI improves prediction of outcomes. A cohort of906 breast cancer patients diagnosed at Henry Ford Health System, Detroit (1985-1990) were studied. The median follow-up was 10 years. Multivariate logistic …
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Exploring the experience of advanced recurrence in people with cancer who perceived themselves as cancer free : a grounded theory study
… Evolving treatment options for people with cancer mean that increased numbers survive after diagnosis and enter a period where they perceive themselves as cancer free. Unfortunately, some experience a cancer recurrence, which can be at an advanced stage. Their prior treatment experience may …
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Surguvant inflammation and metabolism in colorectal surgery
… the perioperative period may predispose to colon cancer recurrence. This thesis examined the ability to harness perioperative body composition, cell free DNA (cfDNA) and metabolomic data and apply these as prognostic markers and potential therapeutic targets in the treatment of colon cancer. …
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Experiences of patients and of partners of patients with a recurrence of colorectal cancer: a qualitative longitudinal study
Colorectal cancer is the fourth most common cancer type in the UK. Following treatment, many patients will recover and be considered cured. However, this is not the case for all patients and some will face a recurrence of their cancer. This PhD aimed to explore the experiences of patients and …
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Treatment Side Effects & Nonadherence among Women Taking Adjuvant Endocrine Therapy for Breast Cancer: The Role of Psychological Factors
… significantly increases the risk of breast cancer recurrence. Side effects are a key driver of nonadherence to these treatments. As part of this doctoral research, two studies were conducted to explore the possibility that psychological factors contribute to both the experience of side …
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Identification of novel biomarkers for clinical prognosis in breast cancer
… signalling is up-regulated in numerous human cancers (e.g. stomach cancer, colon, rectal, glioblastoma, ovarian, renal, lung and breast) making S1P signalling an important candidate as a biomarker and a key player in promoting cancer progression. Several inhibitors of SK/S1P signalling pathway …
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Microarray-based gene set analysis in cancer studies
… of biological mechanisms underlying breast cancer recurrence. In the third part, statistical models for analyzing combined microarray-based expression and genomic copy number data are developed. In addition, an analysis which incorporates tumour subgroups is shown to provide more accurate …
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Y-box binding protein-1 (YB-1) is a bio-marker of aggressiveness in breast cancer and is a potential target for therapeutic intervention
… important factors for successful treatment of cancer. Currently, scientists are searching for molecular markers that can help identify and predict outcome and chance of recurrence in patients. In this study, we demonstratet he potential impact of Y-Box binding protein-1 (YB-1) as a marker of …
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I'm So Happy, But Also Terrified: The Experiences of Women with a History of Cancer During the Perinatal Period
Young female cancer survivors are at a disproportionate risk of suffering psychological distress following treatment, particularly fears of cancer recurrence (FCR). While previous research has established the robust relationship between FCR and family matters (e.g., fertility and motherhood), there …
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A Randomized Non-Inferiority Trial of Technician-Guided and Self-Guided Transdiagnostic Internet-Delivered Cognitive Behaviour Therapy for Cancer Survivors: Making Treatment Scalable
Many cancer survivors face difficulties adjusting to life after cancer; approximately 14-24% of cancer survivors experience clinical problems with anxiety, depression, and/or worry about the future. Depression and anxiety have significant consequences for survivors in terms of distress, quality of …
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Cultivating Quality of Life: Assessing Diet, Physical Activity, and Mental Health Among Arab-American Breast Cancer Survivors - Uncovering Barriers and Facilitators for Holistic Well-Being
… the quality of life among Arab-American breast cancer survivors, with a particular emphasis on dietary practices, physical activity, and mental health. Despite increasing survivorship rates in this population, there remains a significant gap in the literature addressing their unique …
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A COMPREHENSIVE OVERVIEW OF PSYCHOLOGICAL AND ETHICAL IMPLICATIONS ON THE ROLE OF CAREGIVER IN THE CLINICAL PATHWAY OF PATIENTS NEWLY DIAGNOSED WITH BREAST AND PROSTATE CANCER
… involvement in the Shared Decision-Making and cancer care has burgeoned in the psychological field; however, knowledge gaps still exist because most studies have failed to acknowledge the multidimensional nature of agreement/disagreement among dyads in the Shared Decision-Making and cancer …
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Reservoir-based devices for the monitoring and treatment of disease
Cancer mortality still remains high despite significant investments in diagnostics, drug development, and treatment. The systemic route is convenient both for routine monitoring and for drug administration. Local cancer biomarker concentrations, however, are more indicative of the state of solid …
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Defining and Targeting Epigenetic Rewiring During Tumor Progression
<p>Tumor recurrence following initial treatment is the leading cause of death among breast cancer patients. Epigenetic mechanisms are critical for regulation of gene expression and to facilitate appropriate responses to environmental cues. However, it is increasingly appreciated that epigenetic …
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Induction of Immunogenic Cell Death via Nanoparticle-Mediated Dual Chemotherapy and Photothermal Therapy
Cancer is the second most common cause of mortality in the world. Several treatment modalities have been developed for cancer therapy. Recently, immune checkpoint (ICP) therapy has demonstrated promising results. However, low response rates, cancer recurrence and side effects are remaining …
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