Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"cancer diagnosis and therapy"”.
-
Novel Optical Endoscopes for Early Cancer Diagnosis and Therapy
… of non-invasively capturing detailed, real time and spatially resolved biochemical information in vivo and thus delineating disease so that non-invasive curative resection or treatment of the affected area can take place. Though visible and near infrared (NIR) light undergo a wide range of …
-
Structure-based design of unnatural glycopeptides for cancer diagnosis and therapy
… glicopéptidos no naturales de MUC1 utilizando un diseño racional basado en estructura. Este trabajo se ha apoyado en datos previamente reportados con el fin de mejorar la afinidad de estos derivados in vitro con anticuerpos bien estudiados, incorporando sustitutos sintéticos de Tn en …
-
Development of non-invasive techniques for bladder cancer diagnosis and therapy
Bladder cancer is among the most common cancers in the UK, responsible for significant patient morbidity. Current techniques for detection suffer from low sensitivity, particularly for early stage disease, therefore new techniques are urgently sought.<br/><br/>Among the suggested techniques to …
-
Design strategies and application of stimuli-responsive nanoparticles for cancer diagnosis and therapy
Small molecule anticancer drugs are the first-line therapy used in clinical cancer management which has shown success in the killing of rapidly dividing cancer cells. However, nonspecific distribution of these small molecular therapeutics has adverse side effects reducing the quality of life. …
-
The biodistribution of monoclonal antibodies and effector cells : pharmacokinetic modeling and its role in cancer diagnosis and therapy
Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1996.
-
An Electrospray Solution to the Pulmonary Delivery Problem
… tissues via a bronchoscope. Novel diagnostic and therapeutic interventions are now possible by delivering appropriate molecules to target sites. The impact of this thesis is to facilitate earlier diagnosis of lung disease and enable local delivery of therapeutics to the lungs. Delivering …
-
Fighting cancer with nanomedicine−drug-polyester nanoconjugates for targeted cancer therapy
… uptake by reticuloendothelial system (RES) and facilitate targeted cancer diagnosis and therapy. By uniquely integrating well-established chemical reaction-controlled ring opening polymerization (ROP) with nanoprecipitation technique, I successfully developed a polymeric NC system based on …
-
Complex Plasmonic Nanostructures: Symmetry Breaking and Coupled Systems
… resonant oscillations of their conduction band electrons called localized surface plasmon resonances. Plasmons couple efficiently to light and have enabled a new class of technology for the manipulation of light at the nanoscale. Nanostructures that support plasmon resonances have the …
-
Biochemical and Molecular Characterization of the Prostate-Specific Membrane Antigen (PSMA)
<p>Prostate cancer is the most common malignancy and the second leading cause of cancer death in males in the United States. Additionally, the number of deaths attributed to prostate cancer is increasing at a rate of approximately 8% a year. Development of new diagnostic and therapy strategies are …
-
Precisely size controlled drug-silica nanoconjugate for cancer therapy
… a new type of drug delivery system for improved cancer therapy. By using such monodisperse, drug-containing NPs with discrete and incremental difference in sizes, my aim is to study and elucidate the existing relationships among particle size, biologic processing, and therapeutic functionality …
-
Quantitative mRNA detection with advanced nonlinear microscopy
<p>Cell-specific information on quantity and localization of key mRNA transcripts in single-cell level are critical to the assessment of cancer risk, therapy efficacy, and effective prevention strategies. While current techniques are not capable to visualize single mRNA transcript beyond the …