Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 11373 for “"cancer"”.
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Human papillomaviruses in skin cancer and cervical cancer
… papillomavirus (HPV) and development of cervical cancer is well established. In contrast, the significance of infections with cutaneous HPV for development of non-melanoma skin cancer (NMSC) is not well understood. We have evaluated whether seropositivity to cutaneous HPV is a marker for cutaneous …
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Cancer Cartography: Mapping Cancer Evolution in Tissue Space
… evolution is widely accepted as fundamental to cancer development, significant gaps in understanding persist. These gaps concern the role of cellular interactions within the tumour microenvironment (TME) and the impact of spatial constraints on cancer evolution. Emerging spatial omics …
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Oral cancer
Ο καρκίνος του στόματος αποτελεί ένα σημαντικό παγκόσμιο πρόβλημα υγείας με σημαντικές ιατρικές, κοινωνικές και οικονομικές επιπτώσεις. Παρά τις βελτιώσεις στην πρόληψη, τη διάγνωση και τη θεραπεία, εξακολουθεί να συνδέεται με υψηλή νοσηρότητα και θνησιμότητα, κυρίως λόγω της καθυστερημένης …
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Marital adjustment of older adult couples with breast cancer, prostate cancer, and couples without cancer
… adjustment of older adult couples with breast cancer, prostate cancer, and couples who have experienced neither. Participants were 64 couples in which at least one of the spouses was over 55 years of age, including 19 breast cancer couples, 20 prostate cancer couples, 25 couples who had …
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Associations Between Personal Cancer History and Lung Cancer Risk
… relationship between factors related to personal cancer history and lung cancer risk as well as assess their predictive utility. Characteristics of interest included the number, anatomical site(s), and age of onset of previous cancer(s). Data from the Prostate, Lung, Colorectal and Ovarian …
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Inflammation enhanced colon cancer & natural anti-cancer plant compounds
… associated with an increased risk for colorectal cancer through mechanisms that are not well understood. Isothiocyanates, which are the bioactive components in broccoli and other cruciferous vegetables, have been shown to suppress COX-2 and IL-6 production from inflammation. The polyacetylene …
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The host response to cancer and cancer-associated cachexia
… syndrome, affects up to 90% of patients with cancer and causes significant morbidity and mortality worldwide. Patients with cachexia suffer from weight loss, anorexia, sarcopenia, and behavioural changes that eventually lead to death. Given its incidence and prevalence, its negative impact on …
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Role of cancer stem cells in breast and prostate cancer
Cancer stem cells (CSC) are thought to be responsible for the initiation, propagation and tumour re-occurrence. CSC have been identified in most solid and haematological cancers and account for ~1% of the total cell population. Culturing cancer cell lines in monolayers enriches for the most …
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Cancer : emotional experiences
Cancer can have major implications for those who receive a diagnosis, not only as a result of its physical impact, but its emotional one. The emotional impact can not only be distressing in itself, it can also affect behaviour and therefore, has been linked to poorer treatment adherence. The …
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Mismatch Repair Deficient Cancer Diagnostic Aspects in Colorectal Cancer and the Role of Urological Cancer in Lynch Syndrome
… PMS2). The identification of MMR defective colon cancer is clinically relevant for diagnostic, prognostic and potentially also for treatment-predictive purposes. The aims of this thesis were to validate the application of the MMR index for the prediction of MMR deficiency in colon cancer (study …
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Anti-Cancer Effects Of Garcinol In Pancreatic Cancer Transgenic Mouse Model
… diagnosed at early stage. According to American cancer society pancreatic cancer, it has lowest survival rate in all cancer types, with less than 6% five year survival rate. Surgical resection is only possible for 20% of diagnosed cases and current chemotherapy has only 15% response rate. Even …
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Cancer Associated Fibroblast Derived Angiogenic Factor Mfap5 In Ovarian Cancer Progression
<p>Advanced stage ovarian cancer is the most lethal gynecologic malignancy. No major improvement on patient survival has been achieved in the past decade. Therefore, identification of predictive or prognostic markers and further understanding of the molecular mechanisms in ovarian cancer …
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Fighting cancer with nanomedicine−drug-polyester nanoconjugates for targeted cancer therapy
… system (RES) and facilitate targeted cancer diagnosis and therapy. By uniquely integrating well-established chemical reaction-controlled ring opening polymerization (ROP) with nanoprecipitation technique, I successfully developed a polymeric NC system based on poly(lactic acid) and …
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The external morphology of the first zoeal stages of Cancer magister (Dana), Cancer antennarius (Stimpson), and Cancer anthonyi (Rathbun)
… identifies to species any member of the genus Cancer, although one member, C. magister (Dana) is of considerable economic importance on the pacific coast of North America. In the fall of 1958 an investigation was under taken to identify the larval stages of members of the genus Cancer. This …
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The chemokine CCL2/CCR2 signaling mediates cancer associated fibroblasts-cancer cells interaction and promotes basal-like breast cancer progression
Breast cancer is the most common cancer diagnosed in women in the United States. The basal-like breast cancer subtype represents about 12% of breast cancer and has the worst outcome in patients due to lack of effective therapies. Tumor stroma plays an important role in cancer progression. Cancer …
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Surviving Cancer in Appalachia: A Qualitative Study of Family Cancer Communication and Changing Personal Identities Through the Cancer Journey.
… care disparities including higher rates of cancer and premature mortality. Being diagnosed with cancer in the region may present a unique experience for survivors in regards to family cancer communication and changing personal identities. In a multiphasic study, the stories of 29 female …
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Reciprocal communication between cancer cell and tumor microenvironment promotes breast cancer metastasis
… the principle cause of the deaths among breast cancer patients. Brain is one of the major sites of metastasis in breast cancer; however, the pathological mechanism is poorly understood. One of critical steps of brain metastasis is the breaching of the BBB and this process is considered to …
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Exploring Cervical Cancer Treatments, Coping And Sexual Self-Concept After Cervical Cancer
<p>ABSTRACT</p> <p>EXPLORING CERVICAL CANCER TREATMENTS, COPING ADAPTATION AND WOMEN'S SEXUAL SELF-CONCEPT AFTER CERVICAL CANCER</p> <p>By</p> <p>BARBARA G. HOLLIE</p> <p>Cervical cancer survivorship is increasing as a result of improved biomedical science and health care. Due to the nature of …
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Microrna Regulation of Prostate Cancer Stem/Progenitor Cells and Prostate Cancer Development
… of cells with stem cell properties, called cancer stem cells (CSCs), which are believed to be responsible for tumor establishment, metastasis, and resistance to clinical therapy. It’s crucial to understand the regulatory mechanisms unique to CSCs, so that we may design CSC-specific …
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