Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"calpain II"”.
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In vitro proteolysis of ovine lens crystallins by calpain II : A dissertation submitted in partial fulfilment of the requirements for the Degree of Bachelor of Science with Honours
… human blindness worldwide and it is thought that calpain-induced degradation of the major lens proteins, the crystallins, is an important component in many types of cataract.. At Lincoln University, a heritable cataract in sheep is being studied. The aim of this project was to set up an in vitro …
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Design and synthesis and testing of conformationally constrained peptidomimetics.
… Chapter Three introduces cysteine protease calpain II as the primary biological target for this thesis. Calpain is implicated in cataract formation and its inhibition is a logical approach to cataract prevention. Proteases are known to, almost universally, bind substrates and inhibitors in a …
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Non-lysosomal protein degrading systems in chicken skeletal muscle
… the roles played by the ubiquitin-dependent and calpain pathways in protein degradation in chicken skeletal muscles, biochemical studies were conducted on components of these two systems as well as their potential endogenous and exogenous substrates. ATP- and ubiquitin-dependent breakdown of …
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Non-lysosomal protein degrading systems in chicken skeleton muscle
… the roles played by the ubiquitin-dependent and calpain pathways in protein degradation in chicken skeletal muscles, biochemical studies were conducted on components of these two systems as well as their potential endogenous and exogenous substrates. ATP- and ubiquity tin-dependent breakdown of …