Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"calcium-binding proteins"”.
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Characterization of XVEF and XvCaM : two calcium-binding proteins isolated from the resurrection plant Xerophyta viscosa
… overlap extension PCR. XVEF codes for a putative calcium-binding protein and sequence analysis indicated that it has a 708 bp ORF corresponding to a protein with a molecular mass of26.95 kDa, has a conserved calcium-binding EF-hand motif, potential phosphorylation sites, a pI of 6.49 and a …
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An investigation into morphological and biochemical abnormalities in the central nervous system of the mutant mouse tottering
… adult cerebella and the distribution patterns of calcium binding proteins throughout the motor systems of the brain, in two related murine mutants (tottering (tg/tg) and tottering/leaner ($tg/tg\sp{\rm la}$)) and normal age-matched mice.
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Analysis of multiple calmodulin isoforms in Arabidopsis thaliana
… is in part mediated by fluctuations in cytosolic calcium levels. These fluctuations are found to alter the activity of cellular proteins that are sensitive to the calcium levels. The exact nature of signal transduction from external stimuli through calcium is not known, but variations in …
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Classification of Neuronal Nicotinic Acetylcholine Receptors in Rat CA1 Hippocampal Interneuron Subpopulations Defined by Calcium-Binding Protein mRNA Expression
… relative quantitative mRNA expression of three Calcium-binding proteins (CaBPs; calbindin, calretinin, parvalbumin) and eight nicotinic acetylcholine receptor (nAChR) subunits (alpha2-alpha5, alpha7, beta2-beta4) from interneurons from the stratum radiatum or stratum oriens within the CA1 region …
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DRASTIC - INSIGHTS: manipulating gene expression data for formation of hypotheses for plant signal transduction
… opaque to the user.<br/><br/>Genes for proteins involved in the same signal transduction pathway are likely to be coregulated and show the same response to a range of treatments. Thus, to find for example kinases, transcription factors and calcium-binding proteins that are in the same …
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Genomic approaches to understand sweetpotato root development in relation to abiotic factors
… transduction genes, such as those encoding calcium binding proteins (CBP), calcium dependent protein kinases (CDPK) and genes involved in post-transcriptional modifications (protein phosphatase 2A and a phosphatase associated protein) were up-regulated in early developing storage roots in …
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Involvement of Translationally controlled tumor protein in Tomato yellow spot virus infection
… RNAs (siRNAs) by the cleavage of Dicer proteins and the siRNAs generated might regulate the expression of host endogenous genes involves in virus infection. In silico analysis was performed to evaluate the possible siRNAs generated from the silencing of TCTP mRNA, and the respective …
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Structural variations in metal ion complexes of the ligand EGTA⁴-
… for the large preference for EGTA^4- to bind calcium ion rather than (K(CaL^2-) ~= 10^6 magnesium ion = 10^6 (K(MgL^2-)), a preference which is similar to that exhibited by intracellular calcium binding proteins. The alkaline earth compounds, Ca[Ca(EGTA)]·(22/3)H2o, Sr[Ca(EGTA)] ·6H2O, …
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Function of a Unique Dually Localized EF-Hand Domain Containing Protein, TgEFP1, During the Lytic Cycle of the Human Parasite Toxoplasma Gondii
… cycle, which has been shown to be regulated by calcium fluxes. However, little is known about the calcium homeostatic mechanisms utilized by T. gondii. Recently, our lab has identified a novel protein-TgEFP1 (TGGT1_255660), which is predicted to bind Ca2+ through its two EF-hand domains. …
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Struktur und Funktion der afferenten Synapse innerer Haarzellen der Cochlea
… Auch das präsynaptische Cluster von Cav1.3-L-Typ-Calciumkanälen zeigte keine relevanten tonotopen Größenunterschiede. Simulationen lieferten eine Strukturabschätzung, die am ehesten mit einem ovalären Diskus mit einem Längsdurchmesser von etwa 420 nm vereinbar ist. Als weitere Struktur wurde das …
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Investigating the protein targets of the neuroprotective E3 ligase, CHIP
… proteomic analysis revealed that of all the proteins identified and significantly changed between CHIP KO and WT lines, only 35 proteins could be (directly or indirectly) regulated by CHIP. This supports the emerging hypothesis that CHIP can be chaperone-independent docking-dependent E3 …
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Molecular and Ocular Characterization of Novel Fibulin-3 Variants Involved in Retinal Degeneration
Pages xi-xxiv are misnumbered as pages x-xxiii.
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PMCA as a regulator of calcium/calmodulin-dependent signal transduction pathways
Plasma membrane calcium/calmodulin-dependent calcium ATPases (PMCAs) are high affinity calcium pumps regulating many calcium-dependent processes and advances in its characterisation have discovered that it may play a novel role in signal transduction pathways. It was the aim of this work to further …
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Crosstalk Between Calcium Signaling and Lipid Metabolism at Endoplasmic Reticulum-Plasma Membrane Junctions
… PI from the ER to the PM by PI transfer proteins (PITPs) is therefore postulated to support PM PIP2 replenishment. Such transfer is more likely to take place at ER-PM junctions, since the close apposition of the ER and the PM enables PITPs to efficiently interact with two heterologous …
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Unzipping Amyloid Fibrils: How a Novel Calcium-Binding Protein, NUCB1, Prevents the Formation of Amyloid Fibrils
… a widely expressed multi-domain Ca<sup>2+</sup>-binding protein whose precise physiological and biochemical functions are not well understood. We engineered and heterologously expressed a soluble form of NUCB1 (sNUCB1) and characterized its biophysical and biochemical properties. We show that …
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Extending Students' Practice of Metacognitive Regulation Strategies in the Undergraduate Chemistry Laboratory and Investigation of Pb2+ Binding to Calmodulin with Circular Dichroism and Molecular Dynamics Modeling
… the biochemical study on the binding of Pb<super>2+<super> to calmodulin (CaM), data was acquired via circular dichroism (CD) and molecular dynamics modeling. CD signal data indicated a unique signal from Pb-CaM and a significantly smaller ratio θ<sub>208<sub>/θ<sub>222<sub> …