Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"calcium-activated protease"”.
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The effect of calcium activated protease (CAF) and cathepsin D on bovine muscle myofibrils under varying conditions of pH and temperature
<p>This study examined effects of purified CAF and cathepsin D on bovine skeletal myofibrillar proteins and structure when incubated under postmortem-like conditions of pH and temperature;When CAF (purified from bovine cardiac muscle) was incubated with isolated myofibrils under near optimal …
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A Ca²⁺-activated proteinase in chicken skeletal muscle
A neutral calcium-activated protease of muscle (CAP) has previously been characterised and may play a role in myofibrillar disassembly and turnover. In this study both CAP and endogenous CAP inhibitor from adult and embryonic chicken skeletal muscle have been partially purified by DEAE-cellulose …
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Calpain inhibitor design inspired by the natural inhibitor calpastatin
Calpains are cysteine proteases that depend on Ca2+ for activation. They have many roles in the cell; hence modifications of calpains or changes in their levels of activity can lead to altered physiological states. Thus, it is of great interest and medical relevance to design inhibitors that can …
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Novel peptide-based approaches to study the activity and substrate specificity of protein kinases
… Src kinase was found to be cleaved by a calcium-activated protease calpain. In this study, the calpain cleavage site in Src kinase was mapped and a cell-permeable peptide substrate corresponding to this region was demonstrated to have the ability to block calpain cleavage and prevent …