Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"calcium sensors"”.
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Genetically encodable calcium sensors for Magnetic Resonance Imaging
… need for genetically targeted, analyte-specific sensors. Calcium is a molecule of great interest to biology since its fluctuations are highly correlated with neural activity. While much progress has been made in pursuit of genetically encoded calcium sensors none allow for deep tissue imaging of …
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Design and Development of Calcium Sensitive Contrast Agents for fMRI
… be of notable significance to combine MRI with calcium-sensitive contrast agents because of the important role of calcium as a second messenger in cellular signaling pathways. Here we describe a family of calcium sensors for MRI based on the conjugation of superparamagnetic iron oxide …
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Graphene chemical and biological sensors : modeling, systems, and applications
… amplifiers for the first time. Graphene sensors are transitioned to the system level by developing a new sensor array architecture in conjunction with a compact and easy-to-use custom data acquisition system. The system allows for simultaneous characterization of hundreds of sensors and …
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A MULTIORGANELLE PLATFORM REGULATES EGFR ENDOCYTOSIS AND SIGNALLING
… known as tubular invaginations (TIs). Calcium, released from the ER at these sites through the inositol trisphosphate receptor (IP3R), is required, along with the dynamin, for the fission of TIs and the completion of EGFR-NCE. Preliminary data from our laboratory suggested the possible …
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THE INTERPLAY BETWEEN HPCAL4 AND MECP2: IDENTIFICATION AND CHARACTERIZATION OF A NOVEL PUTATIVE TARGET FOR RETT SYNDROME THERAPY
… In this work, we investigated the neuronal calcium sensor hippocalcin-like 4 (Hpcal4), which encodes for a protein belonging to the visinin-like (VSNL) subfamily of EF-hand Ca2+-sensing proteins. Evidence in literature alongside previous transcriptomic data from our laboratory, consistently …
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A Comparative Study of Sensory Neuron Synaptic Activity and the Role of Presynaptic Diversity, Specificity, and Regulation in Caenorhabitis Elegans
… we introduce a reagent for measuring synaptic calcium influx by tethering GCaMP to synaptic vesicles, and we provide our initial characterization of glutamate release in AWC<sup>ON</sup> and ASH. Our results indicate that AWC<sup>ON</sup> and ASH have distinct exocytosis dynamics and that …