Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"calcineurin inhibitors"”.
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Análisis obsevacional para evaluar la eficacia y seguridad de los mTORi en la esfera oncológica en el paciente trasplantado hepático
… death. The immunosuppressant treatment based on calcineurin inhibitor (CNI, tacrolimus, cyclosporine), controls the appearance of rejection but favor the appearance and proliferation of neoplastic cells by relaxation of the immune tumor surveillance. The appearance of mTOR inhibitors (mTORi, …
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Der ELISA-basierte Nachweis von C4d nach Lebertransplantation - ein hilfreicher Marker zur Differentialdiagnose zwischen akuter Abstoßung und rezidivierender Hepatitis-C-Infektion?
… steroid-pulse therapy and/or increased doses of calcineurin-inhibitors. MMF and sirolimus are also state of the art in treatment of rejection reactions. However, acute rejection accounts for the majority of complications (20-40%) in the process of liver transplantation. Hepatitis-C-induced liver …
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The calcineurin inhibitor cyclosporine A activates the renal Na-(K)-Cl cotransporters via local and systemic mechanisms
The two calcineurin inhibitors (CNIs) cyclosporine A (CsA) and tacrolimus are potent immunosuppressive drugs that have become indispensable in the post-transplantational therapy and in the treatment of autoimmune diseases. Immunosuppression via CNIs is achieved by inhibition of the calcineurin …
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Sexual Reproduction and Signal Transduction in the Candida Species Complex
… the second and third chapters we examine the calcineurin signaling pathway, which is crucial for mediated tolerance to cellular stresses including cations, azole antifungals, and passage through the host bloodstream. First, we show that clinical use of calcineurin inhibitors in combination …
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PKB/Akt : a critical regulator of lymphocyte, development and function
… were also less sensitive to inhibition by the calcineurin inhibitors CsA or FK506, which indicates the proliferative response of myr PKB tg T cells is relatively independent of calcium mobilisation and calcineurin activity. In addition, when TCR signalling was inhibited by the MEKinase …
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Bedeutung der Interaktion von Calcineurin und SORLA für die Regulation des Na⁺,K⁺,2Cl⁻-Kotransporters (NKCC2) in der Niere
… war die ebenfalls im TAL exprimierte Phosphatase Calcineurin Aβ (CnAβ) per Western blot um das zweifache gesteigert. Parallel hierzu wurde immunhistochemisch die Kolokalisation von verstärktem CnAβ-Signal und NKCC2 bestätigt. Beide Befunde geben zusammen den Hinweis auf einen Bezug zwischen der …