Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"cadherin 11"”.
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Osteopontin and Cadherin 11 Are Novel Mediators and Drug Targets For Chronic Lung Diseases
… are incompletely understood. Proteins in the cadherin family contribute epithelial to mesenchymal transition (EMT), a suggested source of myofibroblasts. Cadherin 11 (CDH11) contributes to developmental and pathologic processes that parallel those seen in PF and EMT. Utilizing Cdh11 knockout …
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Angiomotin Is A Novel Cadherin-11 Interacting Protein That Mediates Migration In Prostate Cancer Cells
… in our laboratory showed increased expression of cadherin-11 (Cad11), a mesenchymal cadherin, during PCa progression. Furthermore, Cad11 expression endows PCa cells with increased migratory potential and metastasis to bone. Deletion of the Cad11 cytoplasmic region (cyto) resulted in loss of cell …
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MiR-145 is a tumor suppressor in both tumor progression and metastasis
… miR-145 inhibits cell growth in MCF-7 and HCT-116 cells, it has no significant effect on cell growth in metastatic breast cancer cell lines. However, miR-145 significantly suppresses cell invasion in these cells; in contrast, the antisense oligo against miR-145 increases cell invasion. miR-145 …
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Zell- und molekularbiologische Charakterisierung neuartiger Zell-Zell-Verbindungsarten in Glioma-Zellen und mesenchymalen Stammzellen
… von Transmembran-Glykoproteinen der Cadherin-Großfamilie und damit assoziierten cytoplasmatischen Plaque-Proteinen bestimmt, die meist Actin-Mikrofilamente verankern. Sie stellen Hauptstrukturelemente des spezifischen Gewebe-Aufbaus und Zusammenhalts dar und sind darüberhinaus auch an …
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Investigation of p75 neurotrophin receptor and the role of its post-translational modifications in tumour cell motility and invasiveness
… cell migration and invasion, such as cadherin 11 and matrix metalloproteinase 12. Analysis of potential transcription factor binding sites revealed that transcription of these genes might be regulated by well known p75NTR signalling cascades such as NF-κB or JNK signalling, which are …
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Determining Mechanisms by which Pathological Extracellular Matrix induces Ocular Hypertensive Phenotypes in Human Trabecular Meshwork Cells
… shuttling of inactive β-catenin, reduced Cadherin-11, and key Wnt target genes/proteins; and increased cytoplasmic TAZ levels, reduced YAP levels in the nucleus and critical YAP/TAZ target genes/proteins. Wnt activation rescued hTM cells from 10%XCDM-induced stiffening correlated with …
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Contributions of type 2 IP3 receptors to intercellular adhesions and invasion of glioblastoma cells
… analysis suggested that the adhesion molecules N-cadherin, Cadherin 11 and NCAM are upregulated due to a reduction in IP3R2. Hypoxia has been shown to reduce IP3R2 protein levels, reduce cell-to-cell adhesion, and increase invasion in U87-MG cells. Therefore, hypoxia was included in the RNA-seq …
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Selective Isolation of Circulating Tumor Cells in Antibody-Functionalized Microsystems
… non-target BT-20 cells were driven through anti-cadherin-11 functionalized microchannels to study the selective isoaltion of target cells from binary mixtures. The system sensitivity is very high, above 0.95, while the specificity is only moderately high, about 0.85, essentially independent of …