Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 128 for “"cGMP"”.
-
The roles of nitric oxide,cGMP, and cGMP-dependent protein kinase in generation and modulation of circadian rhythms by the suprachiasmatic nucleus
ETDs are only available to UIUC Users without author permission
-
Identifizierung und Funktion von Effektorproteinen der NO/cGMP Signalkaskade
… die lösliche Guanylylzyklase und führen über den cGMP/cGMP-Kinase abhängigen Signalweg zur Erschlaffung der glatten Muskulatur. Wie die Kinase dieses Signal vermittelt ist noch weitgehend unklar, wobei schon einige Substrate der cGMP-Kinase I bekannt sind. In der Mikrosomenfraktion glatter Muskeln …
-
Hypergravitationsinduzierte Effekte auf cGMP-Konzentration humaner Melanozyten und Melanomzellen
… As guanosine 3',5'-cyclic monophosphate (cGMP) is known to play an important signaling role in human melanocytes and different guanylyl cyclase isoforms are responsible for the cGMP synthesis in nonmetastatic and metastatic melanoma cells, the effects of hypergravity on the regulation of …
-
cGMP Training Programs: Understanding the Effects of Cognitive Load
… The current Good Manufacturing Practices (cGMP) regulations require that training be conducted on cGMPs on a periodic basis. However, the cGMPs are complex, comprehensive and tedious and the training on cGMPs is notoriously boring. Cognitive Load Theory has helped to improve instructional …
-
Untersuchungen zur Regulation des Glucosetransportes durch cGMP in isolierten Herzmuskelzellen adulter Ratten
… points to a potential role of cyclic GMP (cGMP) in the control of cardiac glucose utilization. The present work examines whether the glucose transport system of cardiac myocyte is a site of this cGMP-dependent regulation. Treatment of isolated rat cardiomyocytes (for 10 min) with the …
-
Analyse Gewebe-spezifischer Deletionen der cGMP-abhängigen Proteinkinase Typ I in Mäusen
… dass NO die Synthese des "second Messengers" cGMP bewirkt, welcher die cGMP-abh?xE4;ngige Proteinkinase Typ I (cGKI) aktiviert. Um die in vivo-Funktion der cGKI aufzukl?xE4;ren, wurden bereits konventionelle cGKI Knockout M?xE4;use generiert und analysiert. Da diese Nullmutanten einen …
-
Molecular Characterisation of the Brassinosteroid, Phytosulfokine and cGMP-dependent Responses in Arabidopsis thaliana
… that these molecules can convert GTP to cGMP in vitro. Secondly, we show that exogenous application of both Phytosulfokine and Brassinosteroid increase changes of intracellular cGMP levels in Arabidopsis mesophyll protoplast demonstrating that these molecules have GC activity in vivo and …
-
Einfluss von Hypergravitation auf den cGMP-Efflux in Stickstoffmonoxid-stimulierten humanen Melanozyten und Melanomzellen
… h) modulates the efflux of the second messenger cGMP under conditions of stimulated cGMP-synthesis. Due to the differential expression of functional guanylyl cyclase (GC) isoforms in normal human melanocytes (NHM) and melanoma cell lines we used direct NO donors (NONOates) which differ in their …
-
Modulation of innate immunity by the cGMP signalling pathway in the drosophila malpighian tubule
… effect is mediated through activation of the cGMP signalling pathway, via interaction with one of its upstream components, soluble guanylate cyclase (sGC), the main intracellular target for NO (Marletta and Spiering 2003). Therefore, the aim of this study was to determine the potential role of …
-
cGMP -Dependent Protein Kinase, Behavioral Plasticity, and Foraging in Honey Bees and Fruit Flies
… phenotype that is affected by a gene encoding a cGMP-dependent protein kinase (PKG, foraging). I accomplish this by using a traditional genetic model---the fruit fly, Drosophila melanogaster , and a traditional behavioral model---the honey bee, Apis mellifera. Variation in the for gene results in …
-
Die Regulation aktivierender und hemmender Signalwege in humanen neutrophilen Granulozyten durch cAMP- und cGMP-erhöhende Vasodilatatoren
… charakterisiertes Substrat der cAMP-PK und der cGMP-PK. Phosphorylierungsversuche mit cAMP-erhöhenden Substanzen ergaben eine rasche, reversible Phosphorylierung dieses Proteins an Ser-157 und Ser-239 in intakten humanen Neutrophilen Granulozyten. Versuche mit cGMP-erhöhenden Substanzen zeigten …
-
Einfluss der löslichen Guanylylzyklase auf die Expression der cGMP-Exporter MRP4 und 5 in humanen Melanomzellen unter Hypergravitationsbedingungen
… mediated by the important second messengers cGMP and cAMP. On the basis of their strategical position in the epidermis, human melanocytes are constantly exposed to mechanical stimuli. That makes them an interesting in vitro system for hyper- and hypogravity studies. Earlier studies showed …
Page 1 of 7