Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"cAMP regulation"”.
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Mrp4 Is a Crucial Regulator of Testosterone Biosynthesis
… where testosterone production is regulated by cAMP, an intracellular second messenger formed when the luteinizing hormone (LH) receptor (Lhr) is activated. As Mrp4 regulates cAMP, we compared testosterone levels in our Mrp4 WT and KO mice. Prepubertal KO mice had significantly reduced …
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Role Of Gravin In Endothelial Wound Healing
… gravin in EC suggests that it may be involved in cAMP regulation by targeting PKA and PDE4 to plasma membrane. Several studies indicate that localization of PKA activity by A-kinase anchoring proteins (AKAPs) to the leading edge and other cytoskeletal regulators is an important factor in cell …
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Testing Whether MRP4 (a cAMP Efflux Pump) and the Beta 2 Andrenergic Receptor (an Upstream Regulator of cAMP Signaling Pathways
… that can efflux the second-messenger, cAMP, from cells. MRP4 has a PDZ interacting motif at its carboxy terminal end through which it binds to scaffolding proteins NHERF1 and PDZK1. Previous studies have shown that PDZK1 serves as a scaffold physically coupling MRP4 with the cystic …
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The CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Channel: Anion Permeation, and Regulation by Adenylyl Cyclase and ATP Hydrolysis
<p>CFTR Cl<sup>-</sup> channel function and regulation were studied in guinea-pig ventricular myocytes, using either the whole-cell or excised inside-out patch configurations of the patch clamp technique. A typical myocyte cell membrane contained a total of ~1400 CFTR channels; channel density was …