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Showing 1 to 1 of 1 for “"cAMP/PKA system"”.
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The impact of glucotoxicity on pancreatic β-cell function
… in the islets exposed to chronic hyperglycemia. cAMP analogue or PDE inhibitors counteract these abnormalities and restore β-cell function at least in part, by activating cyclic AMP/PKA system. Using two different diabetic animal models i.e. mild hyperlipidemic ZDF (fa/fa) and hyperglycemic GK …