Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 12 of 12 for “"c2h2 zinc finger"”.
-
Uncovering the Roles of Human C2H2-Zinc Finger Protein ZNF121 in Gene Regulation
… exert regulatory effects, and many DNA-binding C2H2-zinc finger proteins (ZFPs) have recently been shown to be RBPs with roles in mRNA biology. I identified C2H2-ZFP, ZNF121, as a YTHDF2 binding partner in affinity purification and mass-spectrometry (AP-MS) experiments and I hypothesized that, …
-
Protein-DNA Recognition Models for the Homeodomain and C2H2 Zinc Finger Transcription Factor Families
… transcription factor families are the zf-C2H2 and homeodomain TF families. Newly available PBM and B1H specificity models were used to develop recognition models for these two families, with the goal of being able to predict the binding specific of a TF from its protein sequence. We …
-
Glia Delimit Shape Changes Of Sensory Neuron Receptive Endings in C. elegans
… the Otd/Otx transcription factor TTX-1, the C2H2 zinc finger transcription factor ZTF-16, the fusogen AFF-1, and likely the VEGFR-related protein VER-1, all acting within the glial cell. ver-1 expression is induced by dauer entry and by cultivation at high temperature, and requires direct …
-
The study of transcriptional regulation of necrotrophic effector genes ToxA and Tox3 in the wheat pathogen Parastagonospora nodorum
… yeast one-hybrid analysis identified a C2H2 zinc finger transcription factor PnCon7 specifically interacting with Tox3-URE1. Silencing of PnCon7 resulted in the down-regulation of Tox3 in a dose dependent manner. Moreover, pathogenicity and expressions of two other necrotrophic effectors …
-
The study of transcriptional regulation of necrotrophic effector genes ToxA and Tox3 in the wheat pathogen Parastagonospora nodorum
… yeast one-hybrid analysis identified a C2H2 zinc finger transcription factor PnCon7 specifically interacting with Tox3-URE1. Silencing of PnCon7 resulted in the down-regulation of Tox3 in a dose dependent manner. Moreover, pathogenicity and expressions of two other necrotrophic effectors …
-
Discovery and Characterization of the Polycomb Repressive Complex 1 of C. Elegans
… a physical interaction between UNC-3 and the C2H2 zinc finger transcription factor PAG-3, the mammalian homologs of which are coexpressed in olfactory epithelium and hematopoietic cells. Our data explain the locomotory defects of unc-3 mutants and suggest that interactions between unc-3 and …
-
Analysis and characterisation of the mouse Hic2 gene
… (chicken), Hic2 cDNA coded five Krüppel-type C2H2 zinc finger domain. Through the sequencing and comparation with different protein sequences from the homolog proteins from different species (HIC1, Hic1, HIC2, γFBP, and Hypothetical protein), Hic2 protein shares more than 80% homology with …
-
Untersuchungen zu Regulatoren der Flavonoidbiosynthese in Arabidopsis thaliana : eine Studie zu neuen Funktionen bekannter Proteinklassen
… concerning their functions were generated. The C2H2 zinc finger protein TT1 was analysed as an example for a regulator of the seed coat specific proanthocyanidin accumulation. A stable knock out of the tt1 gene was generated using a transposon insertion line and the previously assumed tt1 knock …
-
Comparative analysis of desiccation responses in three Xerophyta species at two stages of seedling development
… Factors (HSFs), A-T hook factors (AHLs), and C2H2 Zinc Finger Proteins (ZATs). The gene ontology enrichment showed that the HSF, AHL, and ZAT motif containing OGs that were up-regulated are involved in water deprivation, abscisic acid response, and oxidative stress response processes, whereas …
-
Analysis and suppression of mutant sel-12 in Caenorhabditis elegans
… suppressors, spr-3 and spr-4, encode nuclear C2H2 zinc finger proteins that have been shown to up-regulate hop-1 transcription in a similar way and thus may be involved in nuclear targeting of the C elegans CoREST complex. sel-12 is also highly expressed in neurons, which suggests that it may …
-
In vivo pool-based shRNA screens to identify modulators of disease progression in hematopoietic malignancies
… a set of hairpins targeting poorly characterized C2H2 zinc finger proteins. While neutral in the in vitro setting, a number of these shRNAs validated as single constructs in vivo. As an additional filter to select candidates for validation, we compared the set of genes targeted by candidate …
-
Deep vertebrate roots for mammalian krab zinc-finger transcription factors
KRAB-associated C2H2 zinc-finger (KRAB-ZNF) proteins are the products of a rapidly evolving gene family that traces back to early tetrapods, but which has expanded dramatically to generate an unprecedented level of species-specific diversity. While most attention has been focused on the more …